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髂嵴和股骨活检中的骨质减少、造血功能及骨重塑:102例股骨颈骨折的前瞻性研究

Osteopenia, hematopoiesis, and bone remodelling in iliac crest and femoral biopsies: a prospective study of 102 cases of femoral neck fractures.

作者信息

Eventov I, Frisch B, Cohen Z, Hammel I

机构信息

Department of Orthopedic Surgery, Tel-Aviv Municipal Government Medical Center, Ichilov Hospital, Israel.

出版信息

Bone. 1991;12(1):1-6. doi: 10.1016/8756-3282(91)90047-m.

DOI:10.1016/8756-3282(91)90047-m
PMID:2054230
Abstract

Cancellous microanatomy, bone remodelling, and hematopoietic tissue were studied in iliac crest and femoral neck biopsies taken intraoperatively in 102 consecutive patients with displaced intracapsular fractures. About half of the femoral biopsies had osteopenia, and most showed replacement of hematopoietic tissue by fat cells, with absence of osteoblasts and osteoclasts. In contrast, most of the iliac crest biopsies showed relatively less decrease in cancellous bone, while hematopoietic tissue and bone remodelling cells were present in approximately 75%. These results indicate that the iliac crest biopsy does not necessarily reflect cancellous microanatomy, hematopoietic tissue, and bone remodelling at other skeletal sites in any given patient.

摘要

对102例连续性关节内移位骨折患者术中获取的髂嵴和股骨颈活检组织进行了松质骨微解剖、骨重塑和造血组织研究。约一半的股骨活检组织存在骨质减少,大多数显示造血组织被脂肪细胞替代,且无成骨细胞和破骨细胞。相比之下,大多数髂嵴活检组织显示松质骨减少相对较少,约75%存在造血组织和骨重塑细胞。这些结果表明,在任何特定患者中,髂嵴活检不一定能反映其他骨骼部位的松质骨微解剖、造血组织和骨重塑情况。

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