β(1-3)葡聚糖基转移酶Gel4p对烟曲霉至关重要。
beta(1-3)Glucanosyltransferase Gel4p is essential for Aspergillus fumigatus.
作者信息
Gastebois Amandine, Fontaine Thierry, Latgé Jean-Paul, Mouyna Isabelle
机构信息
Unité des Aspergillus, Institut Pasteur, 25 rue du Docteur Roux, 75724 Paris Cedex 15, France.
出版信息
Eukaryot Cell. 2010 Aug;9(8):1294-8. doi: 10.1128/EC.00107-10. Epub 2010 Jun 11.
Abstract
The beta(1-3)glucanosyltransferase GEL family of Aspergillus fumigatus contains 7 genes, among which only 3 are expressed during mycelial growth. The role of the GEL4 gene was investigated in this study. Like the other Gelps, it encodes a glycosylphosphatidylinositol (GPI)-anchored protein. In contrast to the other beta(1-3)glucanosyltransferases analyzed to date, it is essential for this fungal species.
摘要
烟曲霉的β(1-3)葡聚糖基转移酶GEL家族包含7个基因，其中只有3个在菌丝生长过程中表达。本研究对GEL4基因的作用进行了探究。与其他Gelps一样，它编码一种糖基磷脂酰肌醇（GPI）锚定蛋白。与迄今为止分析的其他β(1-3)葡聚糖基转移酶不同，它对该真菌物种至关重要。
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