从烟曲霉细胞壁中分离出的一种1,3-β-葡聚糖基转移酶是酵母Bgl2p的同源物。
A 1,3-beta-glucanosyltransferase isolated from the cell wall of Aspergillus fumigatus is a homologue of the yeast Bgl2p.
作者信息
Okada Nobuhiko, Tatsuno Lchiro, Hanski Emanuel, Caparon Michael, Sasakawa Chihiro
机构信息
Department of Bacteriology, Institute of Medical Science, University of Tokyo, Tokyo 1 08, Japan.
Department of Clinical Microbiology, The Hebrew University Hadassah Medical School, Jerusalem 91010, Israel.
出版信息
Microbiology (Reading). 1998 Nov;144 ( Pt 11):3079-3086. doi: 10.1099/00221287-144-11-3171.
A 1,3-beta-glucanosyltransferase which introduces intrachain 1,6-beta linkages into 1,3-beta-glucan was isolated from the cell wall of Aspergillus fumigatus. The biochemical and molecular characterization of the A. fumigatus transferase showed it was homologous to the Saccharomyces cerevisiae and Candida albicans transferase Bgl2p. A null mutant constructed in A. fumigatus by gene replacement did not show a distinct phenotype from the parental strain. The putative function of this major cell-wall-associated protein is discussed.
从烟曲霉细胞壁中分离出一种1,3-β-葡聚糖基转移酶，该酶可将链内1,6-β键引入1,3-β-葡聚糖中。对烟曲霉转移酶的生化和分子特性分析表明，它与酿酒酵母和白色念珠菌的转移酶Bgl2p同源。通过基因替换构建的烟曲霉缺失突变体与亲本菌株相比未表现出明显的表型差异。本文讨论了这种主要细胞壁相关蛋白的假定功能。
Zotero 插件