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A20 inhibition of NFκB and inflammation: targeting E2:E3 ubiquitin enzyme complexes.

作者信息

Shembade Noula, Harhaj Edward

出版信息

Cell Cycle. 2010 Jul 1;9(13):2481-2. doi: 10.4161/cc.9.13.12269.

Abstract
摘要

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本文引用的文献

1
Inhibition of NF-kappaB signaling by A20 through disruption of ubiquitin enzyme complexes.
Science. 2010 Feb 26;327(5969):1135-9. doi: 10.1126/science.1182364.
2
Mutations of multiple genes cause deregulation of NF-kappaB in diffuse large B-cell lymphoma.
Nature. 2009 Jun 4;459(7247):717-21. doi: 10.1038/nature07968. Epub 2009 May 3.
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The ubiquitin-editing enzyme A20 requires RNF11 to downregulate NF-kappaB signalling.
EMBO J. 2009 Mar 4;28(5):513-22. doi: 10.1038/emboj.2008.285. Epub 2009 Jan 8.
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A20: central gatekeeper in inflammation and immunity.
J Biol Chem. 2009 Mar 27;284(13):8217-21. doi: 10.1074/jbc.R800032200. Epub 2008 Nov 13.
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Molecular basis for the unique deubiquitinating activity of the NF-kappaB inhibitor A20.
J Mol Biol. 2008 Feb 15;376(2):526-40. doi: 10.1016/j.jmb.2007.11.092. Epub 2007 Dec 4.
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Structural basis for ubiquitin recognition and autoubiquitination by Rabex-5.
Nat Struct Mol Biol. 2006 Mar;13(3):264-71. doi: 10.1038/nsmb1064. Epub 2006 Feb 5.
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De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling.
Nature. 2004 Aug 5;430(7000):694-9. doi: 10.1038/nature02794. Epub 2004 Jul 18.

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