Department of Pediatrics, University of Verona, Verona, Italy.
J Pediatr Gastroenterol Nutr. 2010 Jul;51(1):71-6. doi: 10.1097/MPG.0b013e3181dc8b02.
: Intestinal bacteria play an important role in the postnatal development of the immune system. The composition of gut microbiota is profoundly influenced by the infant's diet, but there is little information about the effects of soymilk on the composition of intestinal biota. The present study was designed to investigate the intestinal ecosystem of the newborn in relation to the consumption of soymilk.
: Twelve infants had their bovine milk-based formula replaced with soymilk. The intestinal microbial composition of the infants was investigated before and after the change by means of polymerase chain reaction-denaturing gradient gel electrophoresis. In addition, species-specific amplification of 10 Bifidobacterium species, 3 Ruminococcus species, and the Bacteroides group was performed.
: Denaturing gradient gel electrophoresis analysis revealed bacterial profiles characterized by numerous bands typical for each subject. No variations were detected by species-specific polymerase chain reaction.
: The data demonstrate that soymilk feeding does not alter the intestinal flora of infants and decrease the intestinal bifidobacterial population.
肠道细菌在免疫系统的出生后发育中起着重要作用。肠道微生物群的组成受婴儿饮食的深刻影响，但关于豆浆对肠道生物群组成的影响的信息很少。本研究旨在调查与豆浆消费有关的新生儿肠道生态系统。
12 名婴儿用基于牛奶的配方奶代替豆浆。通过聚合酶链反应-变性梯度凝胶电泳在更换前后调查婴儿的肠道微生物组成。此外，还进行了 10 种双歧杆菌、3 种瘤胃球菌和拟杆菌组的种特异性扩增。
变性梯度凝胶电泳分析显示出以每个受试者的典型大量条带为特征的细菌图谱。种特异性聚合酶链反应未检测到变化。
数据表明，豆浆喂养不会改变婴儿的肠道菌群，也不会减少肠道双歧杆菌种群。
