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[乙醇对大鼠肝脏胆汁分泌功能的影响]

[The effect of ethanol on the bile-secreting function of the liver in rats].

作者信息

Molostova L V, Agafonova I G, Shustova S G, Mukhina S T, Kartashova N A, Ul'ianova V V

出版信息

Nauchnye Doki Vyss Shkoly Biol Nauki. 1991(3):24-30.

PMID:2054419
Abstract

The effect of long-term application of ethanol on the biochemical composition of rat bile has been studied. These results have been compared with the changes of activity of hepatic microsomal enzymes and ultrastructure of hepatocytes. The changes of biliary lipid synthesis and secretion have been shown to reflect the change of microsomal metabolic functions and to be accompanied by liver destruction processes.

摘要

研究了长期应用乙醇对大鼠胆汁生化成分的影响。将这些结果与肝微粒体酶活性和肝细胞超微结构的变化进行了比较。已表明胆汁脂质合成和分泌的变化反映了微粒体代谢功能的变化,并伴有肝脏破坏过程。

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