Usui Takahiro, Nishimura Eiichi, Soda Mitsutaka, Yaguchi Shigeo, Oniki Hiroaki, Nakano Kiyoko
Department of Ophthalmology, Showa University Fujigaoka Hospital, Japan.
Nippon Ganka Gakkai Zasshi. 2010 May;114(5):429-35.
To evaluate the detrition of clear corneal incisions (CCIs) after intraocular lens (IOL) implantation using an injector system in porcine eyes.
Group A: after CCIs were performed with 1.8, 2.0, 2.2, 2.4, and 2.65 mm wide slit knives, a Y-60 H (HOYA) IOL was implanted in the anterior chamber using an injector system. Group B: after CCIs were performed with 2.4, 2.65, 2.8, 3.0, and 3.2 mm wide slit knives, a PY-60 R (HOYA) IOL was implanted in the anterior chamber using an injector system. Group C: after CCIs were performed with 2.8, 3.0, 3.2, 3.4 mm wide slit knives, a SN 60 AT (Alcon) IOL was implanted in the anterior chamber using an injector system.
CCIs were performed with 3.0 mm wide slit knives. Each group used five porcine eyes for each slit knife (Group A 25 eyes; Group B 25 eyes; Group C 20 eyes; CONTROL 5 eyes). The detrition of the CCIs was evaluated on three different aspects using a scanning electron microscope: a) external expansion at both edges of CCIs; b) rupture of the collagen fibers; c) expansion between the collagen fibers. Aspects a, b and c were given a score of 0, 1, and 2, respectively, and the total points were compared statistically between test and control groups.
The degree of CCIs detrition was significantly reduced in CCIs with a width of more than 2.4 mm of CCIs width in Group A, more than 3.0 mm in Group B, and more than 3.2 mm in Group C.
Minimizing the detrition of corneal incisions after IOL implantation needs a larger than the recommended width of corneal incision.
使用注射器系统在猪眼中评估人工晶状体(IOL)植入术后透明角膜切口(CCI)的磨损情况。
A组:使用1.8、2.0、2.2、2.4和2.65毫米宽的裂隙刀制作CCI后,使用注射器系统将Y-60 H(豪雅)人工晶状体植入前房。B组:使用2.4、2.65、2.8、3.0和3.2毫米宽的裂隙刀制作CCI后,使用注射器系统将PY-60 R(豪雅)人工晶状体植入前房。C组:使用2.8、3.0、3.2、3.4毫米宽的裂隙刀制作CCI后,使用注射器系统将SN 60 AT(爱尔康)人工晶状体植入前房。
使用3.0毫米宽的裂隙刀制作CCI。每组每种裂隙刀使用5只猪眼(A组25只眼;B组25只眼;C组20只眼;对照组5只眼)。使用扫描电子显微镜从三个不同方面评估CCI的磨损情况:a)CCI两边的外部扩张;b)胶原纤维的断裂;c)胶原纤维之间的扩张。方面a、b和c分别给予0、1和2分,并对试验组和对照组的总分进行统计学比较。
A组中CCI宽度大于2.4毫米、B组中大于3.0毫米、C组中大于3.2毫米的CCI,其磨损程度显著降低。
将人工晶状体植入术后角膜切口的磨损降至最低需要比推荐的角膜切口宽度更大的切口宽度。