Chatrenet P, Milan C, Arveux P, Piard F, Dusserre-Guion L, Faivre J
Registre des tumeurs digestives (équipe associée INSERM-DGS), faculté de médecine, Dijon, France.
Bull Cancer. 1991;78(3):229-35.
The data of the polyp registry of the Côte d'Or was used to study the characteristics of hyperplasic polyps detected in a well defined-population. In the 1976-1985 10-yr period, 1,222 hyperplasic polyps were resected in 874 Côte d'Or residents. They represented 17% of all polyps. The incidence rate standardized according to the world reference population was 21.9/100,000 in males and 8.1/100,000 in female. The male predominance was observed in all age groups. The incidence of hyperplasic polyps increased by a mean of 19.8% per year in males and 26.6% in females (P less than 0.001). Hyperplasic polyps were discovered twice as often in patients living in an urban area than in patients living in a rural area (P less than 0.001). Hyperplasic polyps were smaller than 5 mm in 91.4% of cases and were located in the rectum in 59.4% of the cases. They were associated with an adenoma in 21.0% of the cases. In the case of a rectal hyperplasic polyp, 10.5% of the patients had an adenoma in the left colon and 2.8% in the right colon. A rectal hyperplasic polyp cannot be considered as a marker of the presence of a large bowel adenoma. The relationship between hyperplasic polyp and colorectal cancer needs to be established.
使用科多尔省息肉登记处的数据来研究在明确界定人群中检测到的增生性息肉的特征。在1976年至1985年这10年期间,874名科多尔省居民切除了1222个增生性息肉。它们占所有息肉的17%。根据世界参考人群标准化后的发病率在男性中为21.9/10万,在女性中为8.1/10万。在所有年龄组中均观察到男性占优势。男性增生性息肉的发病率平均每年增加19.8%,女性增加26.6%(P<0.001)。城市地区居民发现增生性息肉的频率是农村地区居民的两倍(P<0.001)。91.4%的病例中增生性息肉小于5毫米,59.4%的病例位于直肠。21.0%的病例中它们与腺瘤相关。在直肠增生性息肉的病例中,10.5%的患者左结肠有腺瘤,2.8%的患者右结肠有腺瘤。直肠增生性息肉不能被视为大肠腺瘤存在的标志物。增生性息肉与结直肠癌之间的关系有待确定。