Goldstein D P
Int J Gynaecol Obstet. 1977;15(3):207-15. doi: 10.1002/j.1879-3479.1977.tb00676.x.
This article reviews worldwide controversies concerning gestational trophoblastic neoplasms (hydatidiform mole, invasive mole, and choriocarcinoma). The epidemiology, endocrinology, histopathologic grading, classification, diagnosis, treatment, management and follow-up (including chemotherapy, irradiation, and immunotherapy) of gestational trophoblastic neoplasms - particularly molar pregnancies - are discussed; and ways to help create a standardized classification system and provide optimal treatment for each type of patient are suggested.
本文综述了全球范围内关于妊娠滋养细胞肿瘤（葡萄胎、侵蚀性葡萄胎和绒毛膜癌）的争议。讨论了妊娠滋养细胞肿瘤，尤其是葡萄胎妊娠的流行病学、内分泌学、组织病理学分级、分类、诊断、治疗、管理及随访（包括化疗、放疗和免疫治疗）；并提出了有助于建立标准化分类系统及为各类患者提供最佳治疗的方法。
