Concordia University, CA, USA.
J Pers Disord. 2010 Jun;24(3):392-404. doi: 10.1521/pedi.2010.24.3.392.
Depressive personality disorder (DPD) is currently included in the DSM-IV Appendix B, Criteria Sets and Axes Provided for Further Study. Evidence of the clinical utility of DPD will likely play an important role in the determination of whether it warrants inclusion in future editions of DSM. The current investigation examines the capacity of DPD traits to predict overall and preferential treatment outcome for patients with Major Depressive Disorder (MDD) (N = 120) using data from a randomized control trial, which included cognitive behavioral therapy (CBT), interpersonal therapy (IPT), and antidepressant medication (ADM) treatment arms. Patients were treated for 16-20 weeks and completed the Structured Clinical Interview for DSM-IV Axis II Personality Disorders Questionnaire (SCID-II/PQ) and the 17-item Hamilton Rating Scale for Depression immediately before and after treatment. Higher scores on a dimensionalized SCID-II/PQ subscale assessing DPD traits were associated with poor outcome for IPT, but not CBT or ADM. This result remained after accounting for variance associated with other personality disorder (PD) traits; none of the other 10 main text PDs predicted treatment outcome.
抑郁型人格障碍（DPD）目前被列入 DSM-IV 附录 B，即进一步研究的标准集和轴。DPD 的临床实用性证据可能在确定其是否值得纳入 DSM 的未来版本中发挥重要作用。本研究使用来自一项随机对照试验的数据，检查 DPD 特征预测伴有或不伴有抗抑郁药物治疗的重度抑郁障碍（MDD）患者（N=120）的总体和偏好治疗结果的能力，该试验包括认知行为疗法（CBT）、人际心理疗法（IPT）和抗抑郁药物（ADM）治疗组。患者接受 16-20 周的治疗，并在治疗前后立即完成 DSM-IV 轴 II 人格障碍问卷（SCID-II/PQ）和 17 项汉密尔顿抑郁评定量表（HAMD）。在考虑到其他人格障碍（PD）特征相关的变异性后，SCID-II/PQ 评估 DPD 特征的维度评分越高，与 IPT 治疗效果不佳相关，但与 CBT 或 ADM 无关。这一结果在考虑了其他 10 种主要文本 PD 无预测治疗结果的情况下仍然存在。
