Király E, Jancsó G, Hajós M
Department of Anatomy, Albert Szent-Györgyi Medical University, Szeged, Hungary.
Brain Res. 1991 Feb 1;540(1-2):279-82. doi: 10.1016/0006-8993(91)90518-z.
The changes in the fine structure of axonal profiles of the guinea-pig ureter were examined after exposure to capsaicin in vitro. In the ureters exposed to capsaicin (1-10 microM), about 60%, of all axonal profiles exhibited conspicuous ultrastructural impairment. It is suggested that these alterations might interfere with the release of peptides from these particular nerve endings and therefore contribute significantly to the mechanisms of capsaicin desensitization.
在体外暴露于辣椒素后，对豚鼠输尿管轴突轮廓的精细结构变化进行了检查。在暴露于辣椒素（1 - 10微摩尔）的输尿管中，所有轴突轮廓中约60%表现出明显的超微结构损伤。提示这些改变可能会干扰这些特定神经末梢肽的释放，因此对辣椒素脱敏机制有显著贡献。
