Drum B A, Severns M, O'Leary D K, Massof R W, Quigley H A, Breton M E, Krupin T
Appl Opt. 1989 Mar 15;28(6):1135-44. doi: 10.1364/AO.28.001135.
A new perimetric pattern discrimination test was compared with conventional automated perimetry (Humphrey program 30-2 or Octopus program 32) in glaucoma patients, glaucoma suspects, and control subjects. The new test is based on the rationale that a greater percentage of retinal ganglion cells should be needed to detect a stimulus by its shape, or pattern, than by its brightness. The pattern discrimination stimulus was apatch of nonrandom dots embedded in a surrounding random dot field of the same average density. Pattern discrimination thresholds were measured by changing the degree of regularity, or coherence, of the stimulus dots. The fully coherent target was a static, 1-s duration, 20 x 20-dot checkerboard. Using a criterion-free relative operating characteristic analysis, we estimated the ability of both the pattern discrimination and conventional tests to distinguish the normal data distribution from the suspect and glaucoma distributions. The pattern discrimination test appeared to produce separations greater than conventional perimetry for glaucoma suspects and separations equivalent to conventional perimetry for glaucoma patients.
在青光眼患者、青光眼疑似患者和对照受试者中，将一种新的视野模式辨别测试与传统自动视野检查（Humphrey程序30-2或Octopus程序32）进行了比较。新测试基于这样的理论基础：通过形状或模式而非亮度检测刺激时，需要更大比例的视网膜神经节细胞。模式辨别刺激是嵌入具有相同平均密度的周围随机点场中的一片非随机点。通过改变刺激点的规则程度或连贯性来测量模式辨别阈值。完全连贯的目标是一个静态的、持续1秒、20×20点的棋盘格。使用无标准相对操作特征分析，我们估计了模式辨别测试和传统测试将正常数据分布与疑似和青光眼分布区分开来的能力。对于青光眼疑似患者，模式辨别测试产生的区分度似乎大于传统视野检查；对于青光眼患者，其区分度与传统视野检查相当。
