Stewart W C, Connor A B, Rogers G M
Department of Ophthalmology, Medical University of South Carolina, Charleston, USA.
Int Ophthalmol. 1995;19(2):101-7. doi: 10.1007/BF00133180.
We evaluated 19 ocular hypertensive and 32 chronic open-angle glaucoma patients to determine the correlation of pattern discrimination field loss to known markers of glaucomatous damage on the visual field and the optic nerve head. This study found no statistical association of the findings on the pattern discrimination perimeter to the areas of the optic disc, peripapillary halo, peripapillary atrophy, neural rim, or cup/pallor discrepancy (P > 0.05). In addition, no statistical relationship was observed to the diameters of the largest vein or artery in the inferior- or superior-temporal quadrant adjacent to the optic disc (P > 0.05). Between pattern discrimination and automated perimetry no agreement was observed in any visual field cluster (Glaucoma Hemifield Test) greater than that expected by chance alone (P > 0.05). When both visual function tests disagreed, the proportion of abnormal diagnoses in any cluster did not differ statistically between tests in chronic open-angle glaucoma patients (P > 0.05). However, in ocular hypertensive patients a greater proportion of abnormal diagnoses was observed with pattern discrimination perimetry (P < 0.03). This study suggests that pattern discrimination perimetry appears to measure a different physiologic property of the retina than does automated perimetry.
我们评估了19例高眼压症患者和32例慢性开角型青光眼患者,以确定图形分辨视野缺损与视野及视神经乳头青光眼性损害的已知标志物之间的相关性。本研究发现,图形分辨视野计检查结果与视盘面积、视盘周围晕、视盘周围萎缩、神经纤维层或杯盘比/苍白差异之间无统计学关联(P>0.05)。此外,未观察到与视盘相邻的颞下或颞上象限最大静脉或动脉直径之间的统计学关系(P>0.05)。在任何视野簇(青光眼半视野检测)中,图形分辨视野检查与自动视野检查之间的一致性均未超过仅由随机因素预期的一致性(P>0.05)。当两种视觉功能检查结果不一致时,慢性开角型青光眼患者在任何簇中的异常诊断比例在两种检查之间无统计学差异(P>0.05)。然而,在高眼压症患者中,图形分辨视野检查的异常诊断比例更高(P<0.03)。本研究表明,图形分辨视野检查似乎测量的是视网膜与自动视野检查不同的生理特性。