Kwon Yong Hyun, Lee Ga-Young, Kim Won-Serk, Kim Kea Jeung
Department of Dermatology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.
Ann Dermatol. 2009 Feb;21(1):84-7. doi: 10.5021/ad.2009.21.1.84. Epub 2009 Feb 28.
Mycobacterium abscessus (M. abscessus) is an acid-fast bacillus that's classified as a pathogenic "rapid growing" nontuberculous mycobacteria. It is an uncommon cause of human disease, but it can cause skin and soft tissue infection after skin injury following inoculation, minor trauma and surgery. The single most important factor for determining the course and prognosis of a M. abscessus infection is the underlying immune status of the host. We report here on a 71-year-old female who presented with multiple painful erythematous cutaneous nodules on her left forearm. She had diabetes mellitus and had taken oral steroid by herself for two years because of her osteoarthritis. Histologically, granulomas and inflammatory cell infiltration were observed and M. abscessus was identified via the mycobacterial culture. We performed curettage and drainage, followed by 6 months of oral clarithromycin and the patient's disease completely healed.
脓肿分枝杆菌是一种抗酸杆菌,被归类为致病性“快速生长”的非结核分枝杆菌。它是人类疾病的罕见病因,但在接种、轻微创伤和手术后皮肤受伤后可引起皮肤和软组织感染。决定脓肿分枝杆菌感染病程和预后的唯一最重要因素是宿主的基础免疫状态。我们在此报告一名71岁女性,她的左前臂出现多个疼痛性红斑性皮肤结节。她患有糖尿病,因骨关节炎自行服用口服类固醇两年。组织学上,观察到肉芽肿和炎性细胞浸润,并通过分枝杆菌培养鉴定出脓肿分枝杆菌。我们进行了刮除和引流,随后口服克拉霉素6个月,患者的疾病完全治愈。