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与重复手术相关的皮肤马赛分枝杆菌感染的鉴定

Identification of Cutaneous Mycobacterium massiliense Infections Associated with Repeated Surgical Procedures.

作者信息

Cho Ah Young, Kim Yeon Sook, Kook Yoon Hoh, Kim Shin Ok, Back Seung Ju, Seo Young Joon, Lee Jeung Hoon, Lee Young

机构信息

Department of Dermatology, College of Medicine, Chungnam National University, Daejeon, Korea.

出版信息

Ann Dermatol. 2010 Feb;22(1):114-8. doi: 10.5021/ad.2010.22.1.114. Epub 2010 Feb 28.

Abstract

Mycobacterium massiliense, an emerging pathogen that is increasingly reported as a causative agent in infections occurring during medical procedures, is difficult to be identified using conventional methods. Here we report the case of a cutaneous M. massiliense infection that was associated with repeated surgical procedures and that was identified via a comparative sequence analysis of rpoB and hsp65. The patient showed a substantial response to treatment with a combination of antimicrobial therapies consisting of clarithromycin, amikacin, and cefoxitin for 6 months.

摘要

马西利亚分枝杆菌是一种新出现的病原体,越来越多地被报道为医疗程序中发生感染的病原体,使用传统方法很难鉴定。在此,我们报告一例与反复手术相关的皮肤马西利亚分枝杆菌感染病例,该病例通过对rpoB和hsp65进行比较序列分析得以确诊。患者接受了由克拉霉素、阿米卡星和头孢西丁组成的抗菌联合治疗6个月,治疗反应良好。

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