Shin Jung U, Oh Sang Ho, Lee Ju Hee
Department of Dermatology and Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea.
Ann Dermatol. 2010 May;22(2):216-8. doi: 10.5021/ad.2010.22.2.216. Epub 2010 May 18.
Hand-foot-mouth (HFM) disease is primarily a disease of children, although it can be seen in immunocompromised adults. We describe a case of HFM disease in a 35-year-old immunocompetent male. He presented with multiple, 1~2 mm sized, erythematous vesicular papules on both hands and feet. Histopathological findings of a skin biopsy showed superficial perivascular lymphocytic infiltration, focal keratinocyte necrosis, and reticular degeneration. Because delayed diagnosis can cause spread of the disease to children, dermatologists should be aware that HFM disease can occur in adults with intact immune systems.
手足口病主要是一种儿童疾病,不过在免疫功能低下的成年人中也可见到。我们描述了一例发生在一名35岁免疫功能正常男性身上的手足口病病例。他双手和双足出现了多个大小为1至2毫米的红色水疱性丘疹。皮肤活检的组织病理学结果显示有浅表血管周围淋巴细胞浸润、局灶性角质形成细胞坏死和网状变性。由于延迟诊断可能导致疾病传播给儿童,皮肤科医生应意识到手足口病可发生于免疫系统健全的成年人。