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心血管负担及努纳武特(魁北克)因纽特人相关风险因素:环北极因纽特人健康转型队列研究基线结果的启示。

Cardiovascular burden and related risk factors among Nunavik (Quebec) Inuit: insights from baseline findings in the circumpolar Inuit health in transition cohort study.

机构信息

School of Dietetics and Human Nutrition, McGill University, Montreal, Canada.

出版信息

Can J Cardiol. 2010 Jun-Jul;26(6):190-6. doi: 10.1016/s0828-282x(10)70398-6.

Abstract

BACKGROUND

The Inuit are commonly portrayed to be somehow protected from cardiovascular diseases (CVDs) through their traditional lifestyle and diet. However, actual sociocultural transition and related major, modifiable risk factors have scarcely been quantified in the Inuit population. Such knowledge is extremely valuable in terms of public health intervention.

METHODS

A total of 887 Inuit residents from Nunavik, Quebec, participated in a cohort study. The estimates presented were derived from anthropometric and biological measurements gathered at the time of recruitment and enhanced by information collected in the medical file of each participant. All estimates were corrected for a complex sampling strategy and bootstrapped to ensure the representativeness of the general Nunavik population.

RESULTS

Overall, 19% of Inuit had a disease of the circulatory system according to the International Statistical Classification of Diseases and Related Health Problems, 10th revision. Among all disorders, peripheral circulatory system disease was the most prevalent (9%). Prevalences of ischemic heart disease and cerebrovascular disease were of similar magnitude (2.5%). No significant difference in disease prevalence was noted between sexes. The major modifiable CVD risk factors were smoking (84%), obesity (49%) [corrected] (body mass index of greater than 30 kgm2) and elevated blood pressure (13085 mmHg or greater) (18%). Prevalences were globally higher among women.

CONCLUSION

The current belief that the Inuit are protected from CVD is seriously questioned by the results of the present study. Considering the extremely high prevalence of CVD risk factors, a population-based intervention reinforced for women is urgently needed to reduce their risk.

摘要

背景

因纽特人通过传统的生活方式和饮食,被普遍认为在某种程度上免受心血管疾病(CVD)的影响。然而,因纽特人群中实际的社会文化转变和相关的主要可改变的危险因素几乎没有被量化。在公共卫生干预方面,这种知识是非常有价值的。

方法

共有 887 名来自魁北克努纳武特的因纽特人参与了一项队列研究。本研究中的估计值是根据招募时收集的人体测量和生物学测量数据得出的,并通过每位参与者的医疗档案中收集的信息进行了增强。所有估计值均经过复杂的抽样策略校正,并通过自举法进行了校正,以确保努纳武特一般人群的代表性。

结果

总体而言,根据国际疾病分类和相关健康问题第十次修订版,19%的因纽特人患有循环系统疾病。在所有疾病中,周围循环系统疾病最为普遍(9%)。缺血性心脏病和脑血管疾病的患病率相似(2.5%)。男女之间的疾病患病率没有显著差异。主要的可改变的 CVD 危险因素包括吸烟(84%)、肥胖(49%)(体重指数大于 30kg/m2)和血压升高(13085mmHg 或更高)(18%)。普遍而言,女性的患病率更高。

结论

本研究的结果严重质疑了因纽特人免受 CVD 影响的现有观念。考虑到 CVD 风险因素的极高患病率,迫切需要针对女性开展基于人群的干预措施,以降低她们的风险。

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