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耳鸣患者的晚期听觉诱发电位。

Late Auditory evoked potentials in individuals with tinnitus.

机构信息

Speech and Hearing Therapy Program - Department of Physical Therapy, Speech and Hearing Therapy and Occupational Therapy of the Medical School of the University of São Paulo - FMUSP.

出版信息

Braz J Otorhinolaryngol. 2010 Mar-Apr;76(2):263-70. doi: 10.1590/S1808-86942010000200019.

Abstract

UNLABELLED

Long latency auditory evoked potentials (LLAEP) alterations in individuals with tinnitus are suggestive of dysfunction in the central auditory pathways at a cortical level.

AIM

To characterize the LLAEP in individuals with and without tinnitus exposed to occupational noise.

METHOD

Cross-sectional contemporary cohort, prospective study. Sixty subjects exposed to occupational noise, ranging in age from 29 to 50 years underwent LLAEP assessment; 30 of them had tinnitus complaint and 30 did not have tinnitus.

RESULTS

We observed significant statistical difference regarding the mean values of latencies of waves N1 (p<0.001), P2 (p=0.002) and P300 (p=0.039) when we compared individuals with and without tinnitus. In individuals with tinnitus we also noticed a greater number of altered results concerning components N1 (60%) and P2 (66.7%), although only component P2 presented significant statistical difference (p=0.010). For the LLAEP, the latency increase was the only type of alteration found (p=1.000). We found a greater association between bilateral tinnitus and bilateral alteration for all components N1(73%), P2(73%) and P300(50%).

CONCLUSION

It is relevant to study LLAEP in individuals with tinnitus exposed to high occupational sound pressure levels.

摘要

未加标签

患有耳鸣的个体的长潜伏期听觉诱发电位(LLAEP)改变提示皮质水平的中枢听觉通路功能障碍。

目的

描述暴露于职业性噪声的耳鸣和非耳鸣个体的 LLAEP。

方法

这是一项横断面当代队列前瞻性研究。年龄在 29 至 50 岁之间的 60 名暴露于职业性噪声的受试者接受了 LLAEP 评估;其中 30 名有耳鸣主诉,30 名没有耳鸣。

结果

当我们比较有和没有耳鸣的个体时,我们观察到波 N1(p<0.001)、P2(p=0.002)和 P300(p=0.039)的潜伏期平均值有显著的统计学差异。在有耳鸣的个体中,我们还注意到 N1(60%)和 P2(66.7%)成分的改变结果更多,尽管只有 P2 成分有显著的统计学差异(p=0.010)。对于 LLAEP,只有潜伏期增加是唯一发现的改变类型(p=1.000)。我们发现双侧耳鸣与所有成分 N1(73%)、P2(73%)和 P300(50%)双侧改变之间存在更大的相关性。

结论

研究暴露于高职业性声压水平的耳鸣个体的 LLAEP 是很重要的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/82b2/9446206/2252d7da25d8/gr1.jpg

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