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耳鸣与事件相关电位:系统综述。

Tinnitus and event related potentials: a systematic review.

机构信息

Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brazil; Otorrinolaringologia Sul Fluminense (OTOSUL), Volta Redonda, RJ, Brazil.

Faculdade de Medicina de Valença, Volta Redonda, RJ, Brazil.

出版信息

Braz J Otorhinolaryngol. 2020 Jan-Feb;86(1):119-126. doi: 10.1016/j.bjorl.2019.09.005. Epub 2019 Nov 4.

DOI:10.1016/j.bjorl.2019.09.005
PMID:31753780
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9422368/
Abstract

INTRODUCTION

Tinnitus is sound perception in the absence of a sound source. Changes in parameters of latency and amplitude on the auditory event related potentials or long latency potentials waves have been cited in tinnitus patients when compared to a control group.

OBJECTIVE

To perform an assessment of scientific evidence that verifies the possibility of alterations in latency or amplitude of the waves of event related potentials in individuals with tinnitus.

METHODS

By using SciELO, Lilacs, ISI Web and PubMed, scientific databases, a review was performed. Articles published in English, Portuguese, French and Spanish that correlated tinnitus with changes in event related potentials were included in this review.

RESULTS

Twelve articles were located, however only eight fulfilled the criteria for inclusion.

CONCLUSION

The sample of selected studies demonstrate that the long latency auditory evoked potentials related to events between the control and tinnitus patients showed some changes in latency and or amplitude in tinnitus patients. There are changes in event-related potentials when comparing patients with tinnitus and the control group. These changes take place considering the severity of tinnitus, tinnitus site of lesion, and capacity for changes after interventions. The event related potentials can help to determine the neurotransmitter involved in tinnitus generation and evaluate tinnitus treatments.

摘要

简介

耳鸣是指在没有声源的情况下感知到声音。与对照组相比,耳鸣患者的听觉事件相关电位或长潜伏期电位波的潜伏期和振幅参数发生变化。

目的

评估科学证据,以验证耳鸣患者的事件相关电位波潜伏期或振幅改变的可能性。

方法

使用 SciELO、Lilacs、ISI Web 和 PubMed 等科学数据库进行了综述。纳入了与事件相关电位变化相关的耳鸣的英文、葡萄牙文、法文和西班牙文的文章。

结果

共定位到 12 篇文章,但只有 8 篇符合纳入标准。

结论

所选研究样本表明,与对照组相比,与事件相关的长潜伏期听觉诱发电位在耳鸣患者中潜伏期和/或振幅存在一些变化。在比较耳鸣患者和对照组时,事件相关电位会发生变化。这些变化考虑到了耳鸣的严重程度、耳鸣病变部位以及干预后的变化能力。事件相关电位可以帮助确定参与耳鸣产生的神经递质,并评估耳鸣治疗。

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Comparative analysis of acoustic therapies for tinnitus treatment based on auditory event-related potentials.基于听觉事件相关电位的耳鸣治疗声学疗法的比较分析。
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本文引用的文献

1
Involvement of cortico-subcortical circuits in normoacousic chronic tinnitus: A source localization EEG study.皮质-皮质下回路在正常听力慢性耳鸣中的作用:一项脑电信号源定位研究。
Clin Neurophysiol. 2015 Dec;126(12):2356-65. doi: 10.1016/j.clinph.2015.01.027. Epub 2015 Feb 16.
2
The characteristic and changes of the event-related potentials (ERP) and brain topographic maps before and after treatment with rTMS in subjective tinnitus patients.主观耳鸣患者接受 rTMS 治疗前后事件相关电位(ERP)和脑地形图的特征和变化。
PLoS One. 2013 Aug 12;8(8):e70831. doi: 10.1371/journal.pone.0070831. eCollection 2013.
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Neural substrates predicting improvement of tinnitus after cochlear implantation in patients with single-sided deafness.预测单侧聋患者人工耳蜗植入后耳鸣改善的神经基础。
Hear Res. 2013 May;299:1-9. doi: 10.1016/j.heares.2013.02.001. Epub 2013 Feb 13.
4
Neural plasticity expressed in central auditory structures with and without tinnitus.有耳鸣和无耳鸣的中枢听觉结构中的神经可塑性。
Front Syst Neurosci. 2012 May 28;6:40. doi: 10.3389/fnsys.2012.00040. eCollection 2012.
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Tinnitus: Models and mechanisms.耳鸣:模型与机制。
Hear Res. 2011 Jun;276(1-2):52-60. doi: 10.1016/j.heares.2010.12.003. Epub 2010 Dec 10.
6
Late Auditory evoked potentials in individuals with tinnitus.耳鸣患者的晚期听觉诱发电位。
Braz J Otorhinolaryngol. 2010 Mar-Apr;76(2):263-70. doi: 10.1590/S1808-86942010000200019.
7
Alterations in the spontaneous discharge patterns of single units in the dorsal cochlear nucleus following intense sound exposure.强声暴露后耳蜗背侧核单个神经元自发放电模式的改变。
Hear Res. 2009 Oct;256(1-2):104-17. doi: 10.1016/j.heares.2009.07.006. Epub 2009 Jul 19.
8
Alterations in Event Related Potentials (ERP) associated with tinnitus distress and attention.与耳鸣困扰和注意力相关的事件相关电位(ERP)改变。
Appl Psychophysiol Biofeedback. 2008 Dec;33(4):211-21. doi: 10.1007/s10484-008-9065-y. Epub 2008 Oct 3.
9
Residual inhibition functions overlap tinnitus spectra and the region of auditory threshold shift.残余抑制功能与耳鸣频谱以及听觉阈值偏移区域重叠。
J Assoc Res Otolaryngol. 2008 Dec;9(4):417-35. doi: 10.1007/s10162-008-0136-9. Epub 2008 Aug 20.
10
Disruption of balanced cortical excitation and inhibition by acoustic trauma.声学创伤导致皮质兴奋与抑制平衡的破坏。
J Neurophysiol. 2008 Aug;100(2):646-56. doi: 10.1152/jn.90406.2008. Epub 2008 Jun 4.