[紫外线辐射与皮肤色素沉着。芳烃受体——一个“新成员”]
[UV radiation and skin pigmentation. Aryl hydrocarbon receptor - a "new kid on the block"].
作者信息
Esser C, Krutmann J
机构信息
Leibniz-Institut für Umweltmedizinische Forschung gGmbH, Heinrich-Heine-Universität Düsseldorf, Auf'm Hennekamp 50, 40225, Düsseldorf, Deutschland.
出版信息
Hautarzt. 2010 Jul;61(7):561-6. doi: 10.1007/s00105-009-1914-y.
PMID:20549481
Abstract
UV radiation is the most important modulator of skin pigmentation. In this article we report on novel studies which show that the aryl hydrocarbon receptor, which can be activated by UV-generated photoproducts, mediates a substantial part of UVB-induced skin pigmentation reaction. This newly discovered mechanism opens interesting possibilities for cosmetic and therapeutic treatment of pigment disorders.
摘要
紫外线辐射是皮肤色素沉着最重要的调节因素。在本文中，我们报告了一些新的研究，这些研究表明，芳烃受体可被紫外线产生的光产物激活，介导了大部分紫外线B诱导的皮肤色素沉着反应。这一新发现的机制为色素紊乱的美容和治疗开辟了有趣的可能性。
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