Centre de Montpellier, Cemagref, SGMO, 361 rue Jean-François Breton, F-34196 Montpellier, France.
Environ Toxicol. 2010 Oct;25(5):440-5. doi: 10.1002/tox.20588.
The new European regulation on chemicals triggers a huge number of new testing. However, more than 2 years after the enforcement of this policy, toxicity assessment and risk assessment are still using single species tests that deliver little information. As it is often the case, the link between science and policy seems to be disrupted. However, policy makers need more than ever information on the fate and effects of chemicals on living systems. Without relevant knowledge for decision making, the application of the precautionary principle is the only reasonable way to manage risks. It is necessary to develop new risk assessment strategies using the last innovations from biology: the omics tools, ecology, ecosystem modeling, chemistry, and computing. This article highlights some of the recent trends in ecotoxicology and calls for a new research strategy. This strategy implies research to be funded by its users.
新的欧洲化学品法规引发了大量的新测试。然而,在该政策实施两年多后,毒性评估和风险评估仍在使用提供少量信息的单一物种测试。通常情况下,科学和政策之间的联系似乎中断了。然而,政策制定者比以往任何时候都更需要了解化学品在生命系统中的命运和影响的信息。如果没有决策相关的知识,应用预防原则是管理风险的唯一合理方法。有必要利用生物学的最新创新,开发新的风险评估策略:组学工具、生态学、生态系统建模、化学和计算。本文强调了生态毒理学的一些最新趋势,并呼吁制定新的研究策略。该策略意味着由其用户资助的研究。