Frank Diane, Beauchamp Guy, Palestrini Clara
Centre Hospitalier Universitaire Vétérinaire, Faculté de Médecine Vétérinaire, Université de Montréal, St-Hyacinthe, QC J2S 7C6, Canada.
J Am Vet Med Assoc. 2010 Jun 15;236(12):1308-16. doi: 10.2460/javma.236.12.1308.
To systematically review the scientific literature to identify, assess the quality of, and determine outcomes of studies conducted to evaluate the use of pheromones for treatment of undesirable behavior in cats and dogs.
Systematic review.
Reports of prospective studies published from January 1998 through December 2008.
The MEDLINE and CAB Abstracts databases were searched with the following key terms: dog OR dogs OR canine OR cat OR cats OR feline AND pheromone OR synthetic pheromone OR facial pheromone OR appeasing pheromone. A date limit was set from 1998 through 2008. Identified reports for dogs (n = 7) and cats (7) were systematically reviewed.
Studies provided insufficient evidence of the effectiveness of feline facial pheromone for management of idiopathic cystitis or calming cats during catheterization and lack of support for reducing stress in hospitalized cats. Only 1 study yielded sufficient evidence that dog-appeasing pheromone reduces fear or anxiety in dogs during training. Six studies yielded insufficient evidence of the effectiveness of dog-appeasing pheromone for treatment of noise phobia (2 reports), travel-related problems, fear or anxiety in the veterinary clinic, and stress- and fear-related behavior in shelter dogs as well as vocalizing and house soiling in recently adopted puppies.
11 of the 14 reports reviewed provided insufficient evidence and 1 provided lack of support for effectiveness of pheromones for the treatment of undesirable behavior in cats and dogs.
系统回顾科学文献，以识别、评估其质量，并确定为评估信息素用于治疗猫和狗不良行为而开展的研究的结果。
系统回顾。
1998年1月至2008年12月发表的前瞻性研究报告。
使用以下关键词检索MEDLINE和CAB文摘数据库：狗或犬科动物或猫或猫科动物以及信息素或合成信息素或面部信息素或安抚信息素。设定的日期范围为1998年至2008年。对已识别的关于狗（n = 7）和猫（7）的报告进行系统回顾。
研究提供的证据不足，无法证明猫面部信息素对特发性膀胱炎的管理或在导尿过程中使猫平静有效，也无法支持其减轻住院猫的应激反应。只有1项研究提供了充分证据，表明犬类安抚信息素可减轻训练期间狗的恐惧或焦虑。6项研究提供的证据不足，无法证明犬类安抚信息素对治疗噪音恐惧症（2份报告）、旅行相关问题、兽医诊所中的恐惧或焦虑、收容所狗的应激和恐惧相关行为以及新领养幼犬的吠叫和在家中弄脏行为有效。
所回顾的14份报告中有11份提供的证据不足，1份报告不支持信息素对治疗猫和狗不良行为的有效性。
