Translational and Molecular Imaging Institute, Mount Sinai School of Medicine, One Gustave L. Levy Place, Box 1234, New York, NY 10029, USA.
Angiogenesis. 2010 Jun;13(2):131-4. doi: 10.1007/s10456-010-9177-x. Epub 2010 Jun 16.
Quantum dots exhibit unique optical properties for bioimaging purposes. We have previously developed quantum dots with a paramagnetic and functionalized coating and have shown their potential for molecular imaging purposes. In the current mini-review we summarize the synthesis procedure, the in vitro testing and, importantly, the in vivo application for multimodal molecular imaging of tumor angiogenesis.
量子点在生物成像方面具有独特的光学特性。我们之前已经开发出具有顺磁性和功能化涂层的量子点,并展示了它们在分子成像方面的潜力。在当前的小型综述中,我们总结了合成过程、体外测试,以及重要的是,用于肿瘤血管生成的多模态分子成像的体内应用。