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从娃儿藤根中提取的具有抗肿瘤活性的甾体糖苷。

Steroidal glycosides with anti-tumor activity from the roots of Cynanchum wallichii Wight.

作者信息

Chen Gang, Xu Nan, Li Zhi-Feng, Zhang Qi-Hui, Wu Hong-Hua, Pei Yue-Hu

机构信息

School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, China.

出版信息

J Asian Nat Prod Res. 2010 Jun;12(6):453-7. doi: 10.1080/10286020.2010.489821.

Abstract

Two new steroidal glycosides characterized with 2,6-dideoxypyranoses as component sugars have been isolated from roots of Cynanchum wallichii Wight. Their structure elucidation and cytotoxic activities against HL-60 and PC-3 cells are reported.

摘要

从娃儿藤(Cynanchum wallichii Wight)的根中分离出了两种新的甾体糖苷,其特征是以2,6-二脱氧吡喃糖作为组成糖。本文报道了它们的结构解析以及对HL-60和PC-3细胞的细胞毒性活性。

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