来自娃儿藤的两种新甾体糖苷。

Two new steroidal glycosides from Cynanchum wallichii.

作者信息

Wang Ding, Pan Wen-Hao, Bao Yong-Rui, Yang Xin-Xin, Meng Xian-Sheng

机构信息

a Department of Pharmacy , Affiliated Hospital of Liaoning University of Traditional Chinese Medicine , Shenyang 110032 , China.

出版信息

J Asian Nat Prod Res. 2014;16(7):759-63. doi: 10.1080/10286020.2014.915816. Epub 2014 May 2.

DOI:10.1080/10286020.2014.915816

PMID:24786590

Abstract

Two new C21 steroidal glycosides were isolated from Cynanchum wallichii Wight. Their structures were elucidated as caudatin-3-O-β-d-glucopyranosyl-(1 → 4)-β-d-oleandropyranosyl-(1 → 4)-β-d-cymaropyranosyl-(1 → 4)-β-d-digitoxopyranoside (1) and caudatin-3-O-β-d-glucopyranosyl-(1 → 4)-β-d-cymaropyranosyl-(1 → 4)-β-d-oleandropyranosyl-(1 → 4)-β-d-cymaropyranosyl-(1 → 4)-β-d-digitoxopyranoside (2) by spectroscopic methods including 1D and 2D NMR experiments.

摘要

从娃儿藤中分离出两种新的C21甾体糖苷。通过包括一维和二维核磁共振实验在内的光谱方法，确定它们的结构分别为考达定-3-O-β-d-吡喃葡萄糖基-(1→4)-β-d-毛地黄毒糖基-(1→4)-β-d-加拿大麻糖基-(1→4)-β-d-洋地黄毒糖基吡喃糖苷（1）和考达定-3-O-β-d-吡喃葡萄糖基-(1→4)-β-d-加拿大麻糖基-(1→4)-β-d-毛地黄毒糖基-(1→4)-β-d-加拿大麻糖基-(1→4)-β-d-洋地黄毒糖基吡喃糖苷（2）。