来自石韦地上部分的新甾体苷类化合物。
The new steroidal glycosides from the aerial parts of Lepidogrammitis drymoglossoides.
作者信息
Wei Hua, Jiang Hai, Liu Zhu-Xiang, Li Gui, Long Hua, He Jian-Wu, Chen Gong-Xi, Yang Jun-Shan, Ma Guo-Xu
机构信息
a Key Laboratory of Plant Resource Conservation and Utilization (Jishou University) , College of Hunan Province , Jishou 416000 , China.
b Institute of Medicinal Plant Development , Beijing 100193 , China.
出版信息
J Asian Nat Prod Res. 2016 Sep;18(9):878-84. doi: 10.1080/10286020.2016.1171757. Epub 2016 Apr 20.
Two new steroidal glycosides ponasteroside C (1) and ponasteroside D (2) were isolated from the aerial parts of Lepidogrammitis drymoglossoides. Their structures were elucidated by various spectroscopic techniques (IR, HRESIMS, 1D and 2D NMR). All compounds were evaluated for their cytotoxicity against HeLa and HCT-8 cell lines, and compounds 1 and 2 showed mild activity against all the test cell lines.
从石韦的地上部分分离出两种新的甾体糖苷波那甾苷C（1）和波那甾苷D（2）。通过各种光谱技术（红外光谱、高分辨电喷雾电离质谱、一维和二维核磁共振）阐明了它们的结构。评估了所有化合物对HeLa和HCT - 8细胞系的细胞毒性，化合物1和2对所有测试细胞系均显示出轻微活性。
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