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猪(Sus scrofa)在转化生物行为研究中的认知测试。

Cognitive testing of pigs (Sus scrofa) in translational biobehavioral research.

机构信息

Neurobiology Research Unit and Center for Integrated Molecular Brain Imaging, N9201, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, DK-2100 Copenhagen East, Denmark.

出版信息

Neurosci Biobehav Rev. 2011 Jan;35(3):437-51. doi: 10.1016/j.neubiorev.2010.05.004. Epub 2010 May 27.

DOI:10.1016/j.neubiorev.2010.05.004
PMID:20553757
Abstract

Within neuroscience and biobehavioral research, the pig (Sus scrofus) is increasingly being acknowledged as a valuable large animal species. Compared to the rodent brain, the pig brain more closely resembles the human brain in terms of both anatomy and biochemistry, which associates the pig with a higher translational value. Several brain disorders have been fully or partially modeled in the pig and this has further spurred an interest in having access to behavioral tasks for pigs, and in particular to cognitive tasks. Cognitive testing of pigs has been conducted for several years by a small group of farm animal welfare researchers, but it has only recently received interest in the wider neuroscience community. Several behavioral tasks have successfully been adapted to the pig, and valuable results have been produced. However, most tasks have only been established at a single research facility, and would benefit from further validation. This review presents the cognitive tasks that have been developed for pigs, their validation, and their current use.

摘要

在神经科学和生物行为研究领域,猪(Sus scrofus)越来越被认为是一种有价值的大型动物物种。与啮齿动物大脑相比,猪的大脑在解剖学和生物化学方面与人类大脑更为相似,这使得猪具有更高的转化价值。几种脑部疾病已经在猪身上得到了完全或部分建模,这进一步激发了人们对猪进行行为任务的兴趣,特别是认知任务。几年来,一小群农场动物福利研究人员一直在对猪进行认知测试,但最近才引起更广泛的神经科学界的关注。已经成功地对猪进行了几种行为测试,并取得了有价值的结果。然而,大多数任务只在一个研究机构建立,并且需要进一步验证。这篇综述介绍了为猪开发的认知任务、它们的验证以及它们的当前用途。

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