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减肥植物疗法制剂中作为掺杂物的合成药物的存在及其分析测定。

Presence of synthetic pharmaceuticals as adulterants in slimming phytotherapeutic formulations and their analytical determination.

机构信息

Departamento de Química, Universidade Federal de Santa Maria (UFSM), Caixa Postal 5051, CEP 97110-970, Santa Maria, RS, Brazil.

出版信息

Forensic Sci Int. 2011 Jan 30;204(1-3):6-12. doi: 10.1016/j.forsciint.2010.04.045. Epub 2010 May 31.

DOI:10.1016/j.forsciint.2010.04.045
PMID:20554134
Abstract

Obesity that is associated with a high consumption of slimming substances is considered a public health problem around the world. In this context, the increasing consumption of phytotherapeutic formulations as alternative obesity treatments has revealed the presence of synthetic pharmaceuticals as adulterants. The illegally added adulterants are frequently anorexic, anxiolytic, and antidepressant pharmaceuticals. This review aims to describe the analytical methodologies utilized for the determination of adulterants in slimming phytotherapeutic formulations. Furthermore, this review describes some important adulteration cases, which occurred mainly in Europe, Asia, Brazil, and the USA.

摘要

肥胖与大量摄入减肥物质有关,被认为是一个全球性的公共健康问题。在这种情况下,植物疗法制剂作为肥胖治疗的替代方法的消费不断增加,这揭示了作为掺杂物存在的合成药物。非法添加的掺杂物通常是厌食、抗焦虑和抗抑郁药物。本综述旨在描述用于测定减肥植物疗法制剂中掺杂物的分析方法。此外,本综述还描述了一些重要的掺假案例,这些案例主要发生在欧洲、亚洲、巴西和美国。

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