检测城市褐鼠中新的星状病毒和人类中已知的星状病毒。
Detection of novel astroviruses in urban brown rats and previously known astroviruses in humans.
机构信息
State Key Laboratory for Emerging Infectious Diseases, Department of Microbiology and the Research Centre of Infection and Immunology, The University of Hong Kong, Hong Kong SAR.
出版信息
J Gen Virol. 2010 Oct;91(Pt 10):2457-62. doi: 10.1099/vir.0.022764-0. Epub 2010 Jun 16.
Several novel astroviruses have been recently discovered in humans and in other animals. Here, we report results from our surveillance of astroviruses in human and rodent faecal samples in Hong Kong. Classical human astroviruses (n=9) and a human MLB1 astrovirus were detected in human faecal samples (n=622). Novel astroviruses were detected from 1.6 % of the faecal samples of urban brown rat (Rattus norvegicus) (n=441), indicating the prevalence of astrovirus infection in rats might be much lower than that recently observed in bats. These rat astroviruses were phylogenetically related to recently discovered human astroviruses MLB1 and MLB2, suggesting that the MLB viruses and these novel rat astroviruses may share a common ancestor.
最近在人类和其他动物中发现了几种新型星状病毒。在这里，我们报告了在香港对人类和啮齿动物粪便样本中星状病毒进行监测的结果。从人类粪便样本中检测到了经典的人类星状病毒（n=9）和人类 MLB1 星状病毒（n=622）。从城市褐家鼠（Rattus norvegicus）的粪便样本中检测到了新型星状病毒（n=441），这表明星状病毒感染在大鼠中的流行率可能远低于最近在蝙蝠中观察到的水平。这些鼠星状病毒与最近发现的人类星状病毒 MLB1 和 MLB2 具有系统发育关系，提示 MLB 病毒和这些新型鼠星状病毒可能具有共同的祖先。
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