Sorbara Luigina, Maram Jyotsna, Fonn Desmond, Woods Craig, Simpson Trefford
Centre for Contact Lens Research, University of Waterloo, Waterloo, Ontario, Canada.
Clin Exp Optom. 2010 May;93(3):150-6. doi: 10.1111/j.1444-0938.2010.00472.x.
The purpose of the study was to obtain anterior segment biometry for 40 normal eyes and to measure variables that may be useful to design large diameter gas permeable contact lenses that sit outside the region normally viewed by corneal topographers. Also, the distribution of these variables in the normal eye and how well they correlated to each other were determined.
This is a cross-sectional study, in which data were collected at a single study visit. Corneal topography and imaging of the anterior segment of the eye were performed using the Orbscan II and Visante OCT. The variables that were collected were horizontal K reading, central corneal/scleral sagittal depth at 15 mm chord, and nasal and temporal angles at the 15 mm chord using the built-in software measurement tools.
The central horizontal K readings for the 40 eyes were 43 +/- 1.73 D (7.85 +/- 0.31 mm), with +/- 95% confidence interval (CI) of 38.7 (8.7 mm) and 46.6 D (7.24 mm). The mean corneal/scleral sagittal depth at the 15 mm chord was 3.74 +/- 0.19 mm and the range was 3.14 to 4.04 mm. The average nasal angle (which was not different from the temporal angle) at the 15 mm chord was 39.32 +/- 3.07 degrees and the +/- 95%CI was 33.7 and 45.5 degrees. The correlation coefficient comparing the K reading and the corneal/scleral sagittal depth showed the best correlation (0.58, p < 0.001). The corneal/scleral sagittal depth at 15 mm correlated less with the nasal angle (0.44, p = 0.004) and the weakest correlation was for the nasal angle at 15 mm with the horizontal readings (0.32, p = 0.046).
The Visante OCT is a valuable tool for imaging the anterior segment of the eye. The Visante OCT is especially effective in providing the biometry of the peripheral cornea and sclera and may help in fitting GP lenses with a higher percentage of initial lens success, when the corneal sag and lens sag are better matched.
本研究的目的是获取40只正常眼睛的眼前节生物测量数据,并测量一些变量,这些变量可能有助于设计大直径透气性角膜接触镜,使其位于角膜地形图仪通常观察区域之外。此外,还确定了这些变量在正常眼睛中的分布情况以及它们之间的相互关联程度。
这是一项横断面研究,在单次研究访视时收集数据。使用Orbscan II和Visante OCT对眼睛的眼前节进行角膜地形图和成像检查。收集的变量包括水平角膜曲率读数、15mm弦长处的中央角膜/巩膜矢状深度以及使用内置软件测量工具测量的15mm弦长处的鼻侧和颞侧角度。
40只眼睛的中央水平角膜曲率读数为43±1.73D(7.85±0.31mm),95%置信区间(CI)为38.7(8.7mm)和46.6D(7.24mm)。15mm弦长处的平均角膜/巩膜矢状深度为3.74±0.19mm,范围为3.14至4.04mm。15mm弦长处的平均鼻侧角度(与颞侧角度无差异)为39.32±3.07度,95%CI为33.7和45.5度。比较角膜曲率读数和角膜/巩膜矢状深度的相关系数显示相关性最佳(0.58,p<0.001)。15mm处的角膜/巩膜矢状深度与鼻侧角度的相关性较小(0.44,p = 0.004),而15mm处鼻侧角度与水平读数的相关性最弱(0.32,p = 0.046)。
Visante OCT是一种用于眼睛眼前节成像的有价值工具。当角膜矢高和镜片矢高更好匹配时,Visante OCT在提供周边角膜和巩膜生物测量数据方面特别有效,可能有助于提高初次佩戴透气性角膜接触镜的成功率。