Davis Larry E, Guerre Jenny, Gerstein Wendy H
Neurology Service, New Mexico Veterans Affairs Health Care System, 1501 San Pedro Dr SE, Albuquerque, NM 87108, USA.
Arch Neurol. 2010 Jun;67(6):759-60. doi: 10.1001/archneurol.2010.100.
To review the ages of patients with recurrent herpes simplex virus type 2 (HSV-2) meningitis.
Case report and literature review back to 1970.
Referral Veterans Affairs hospital.
Our patient developed his first episode of recurrent HSV-2 meningitis at 78 years of age, 57 years after his only episode of genital herpes simplex infection. Of 223 patients in the literature with recurrent HSV-2 meningitis, 5% occurred in patients older than 60 years and 19% in patients older than 50 years.
Although recurrent meningitis due to HSV is primarily seen in young, sexually active adults, a surprising number of episodes of HSV meningitis can develop in older age. Meningitis due to HSV-2 should be in the differential diagnosis of aseptic meningitis in older patients.
回顾复发性2型单纯疱疹病毒（HSV-2）脑膜炎患者的年龄情况。
病例报告及1970年以来的文献回顾。
转诊的退伍军人事务医院。
我们的患者在78岁时首次发生复发性HSV-2脑膜炎，这是他唯一一次生殖器单纯疱疹感染后的57年。文献中223例复发性HSV-2脑膜炎患者中，5%发生在60岁以上患者，19%发生在50岁以上患者。
虽然HSV所致复发性脑膜炎主要见于年轻、有性活动的成年人，但老年患者中也会出现数量惊人的HSV脑膜炎发作。HSV-2所致脑膜炎应列入老年患者无菌性脑膜炎的鉴别诊断中。
