Enon B, Chevalier J M, Talha H, Lescalie F, L'Hoste P, Pillet J
Service de Chirurgie Vasculaire et Thoracique, Centre hospitalier Régional et Universitaire d'Angers.
J Chir (Paris). 1991 Apr;128(4):182-7.
The study of 44 patients treated with intra-arterial fibrinolysis is reported. All these patients had an impending subacute ischemia of the lower limbs, a major complication of atheromatous disease. The criteria for patient selection were clinical, hemodynamic and radiological. The procedure of the treatment associating Urokinase, Heparin and Naphthidrofluril are defined, as well as its follow-up. The results have been evaluated according to the clinical and radiological improvement. 2 patients died when the treatment ceased and 10 were amputated, ie 27% of failures. The fibrinolytic treatment allowed identifying the patients who might quickly receive an additional treatment. In our experience, this treatment seems to improve the prognosis of impending subacute ischemia.
报告了对44例接受动脉内纤维蛋白溶解治疗患者的研究。所有这些患者均存在下肢亚急性缺血先兆，这是动脉粥样硬化疾病的一种主要并发症。患者选择标准包括临床、血流动力学和放射学标准。定义了联合使用尿激酶、肝素和萘夫西林的治疗程序及其随访情况。根据临床和放射学改善情况对结果进行了评估。2例患者在治疗停止时死亡，10例患者接受了截肢手术，即失败率为27%。纤维蛋白溶解治疗有助于识别可能迅速接受额外治疗的患者。根据我们的经验，这种治疗似乎可以改善亚急性缺血先兆的预后。
