Kim Young-Yul, Rhyu Kee-Won
Department of Orthopedic Surgery, Daejeon St. Mary's Hospital, The Catholic University of Korea, Daejeon, Korea.
Eur Spine J. 2010 Nov;19(11):1907-12. doi: 10.1007/s00586-010-1479-6. Epub 2010 Jun 18.
The purpose of this retrospective clinical study was to evaluate the factors that affect recompression of operated vertebrae after percutaneous balloon kyphoplasty (PKP) for osteoporotic vertebral compression fractures (VCFs) and assess their clinical importance. PKP has been used for VCFs with satisfactory results. Several studies about subsequent VCFs adjacent to cemented vertebrae have been reported after PKP. However, the presence and significance of recompression of operated vertebrae have not been adequately described. In total, 80 patients treated with PKP for single thoracolumbar VCFs were reviewed. The follow-up period was at least 1 year. Patients were divided into those without recompression (maintained group, n = 70) and those with recompression (recompressed group, n = 10). Plain roentgenography (preoperative, operative, and last), preoperative BMD, and preoperative MRI were checked. Age, gender, T-score in BMD, duration of symptom, compression rate (CR) of VCF, reduction rate, kyphotic angle (KA), reduction angle, intervertebral cleft (IVC), and non-PMMA-endplate-contact (NPEC) were evaluated. To evaluate the clinical results, we checked the VAS score at each follow-up period. All data were analyzed statistically. The CR for the recompressed group increased significantly after surgery and decreased at the last follow-up (p < 0.05). The last CR was not significantly different from the preoperative CR. The KA showed the same pattern. The preoperative, postoperative, and last VAS scores were significantly different from one another in both groups (p < 0.05). Between the groups, preoperative KA, postoperative KA, last KA, IVC, and NPEC were significantly different (p < 0.05). In particular, last KA, IVC, and NPEC showed highly significant differences (p < 0.001). In a correlation test for the evaluated factors, IVC (r = 0.557) and NPEC (r = 0.496) were the most significant. The presence of IVC and NPEC may play an important role in inducing recompression of treated vertebrae after PKP. Careful observation of patients with these conditions is necessary to prevent deterioration of their clinical course.
这项回顾性临床研究的目的是评估影响经皮球囊后凸成形术(PKP)治疗骨质疏松性椎体压缩骨折(VCF)后手术椎体再压缩的因素,并评估其临床重要性。PKP已用于治疗VCF,效果令人满意。有几项关于PKP术后相邻椎体随后发生VCF的研究报告。然而,手术椎体再压缩的存在及其意义尚未得到充分描述。总共回顾了80例接受PKP治疗单节段胸腰椎VCF的患者。随访期至少1年。患者分为无再压缩组(维持组,n = 70)和有再压缩组(再压缩组,n = 10)。检查了X线平片(术前、术中及末次)、术前骨密度(BMD)和术前磁共振成像(MRI)。评估了年龄、性别、BMD的T值、症状持续时间、VCF的压缩率(CR)、复位率、后凸角(KA)、复位角度、椎间隙(IVC)和非聚甲基丙烯酸甲酯终板接触(NPEC)。为了评估临床结果,我们在每个随访期检查了视觉模拟评分(VAS)。所有数据进行统计学分析。再压缩组的CR术后显著增加,末次随访时降低(p < 0.05)。末次CR与术前CR无显著差异。KA呈现相同模式。两组术前、术后及末次VAS评分彼此之间均有显著差异(p < 0.05)。两组之间,术前KA、术后KA、末次KA、IVC和NPEC有显著差异(p < 0.05)。特别是,末次KA、IVC和NPEC差异极显著(p < 0.001)。在所评估因素的相关性检验中,IVC(r = 0.557)和NPEC(r = 0.496)最为显著。IVC和NPEC的存在可能在PKP术后诱导治疗椎体再压缩中起重要作用。对有这些情况的患者进行仔细观察对于防止其临床病程恶化是必要的。