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吉兰丹州和登嘉楼州国民服役训练中心野生大鼠钩端螺旋体感染的血清学流行率

Serological prevalence of leptospiral infection in wild rats at the National Service Training Centres in Kelantan and Terengganu.

作者信息

Mohamed-Hassan S N, Bahaman A R, Mutalib A R, Khairani-Bejo S

机构信息

Faculty of Veterinary Medicine, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia.

出版信息

Trop Biomed. 2010 Apr;27(1):30-2.

Abstract

One hundred and sixty eight rats were trapped from the National Service Training Centres (NSTC) in Kelantan and Terengganu from October 2008 to May 2009. Microscopic agglutination test (MAT) was performed to detect the presence of agglutinating antibodies to Leptospira among the rats caught. All the MAT positive rats were identified as Rattus tiomanicus. In Kelantan, 17.3 % (14/81) of the rats had leptospiral antibodies to serovars Icterohaemorrhagiae (12.3%), Canicola (2.5%), Ballum (1.2%), and Pyrogenes (1.2%). In Terengganu, 18.4% (16/87) of the rats had antibodies to serovars Icterohaemorrhagiae (15%), Canicola (1.1%), Pyrogenes (1.1%) and Hebdomadis (1.1%). This study indicated that Leptospira serovars were prevalent in the rat population in the study areas and could be a source of infection to humans. Therefore, control of the rat population in all NSTC is critical to prevent outbreaks of leptospirosis amongst the NSTC trainees.

摘要

2008年10月至2009年5月期间,从吉兰丹州和登嘉楼州的国民服役训练中心(NSTC)捕获了168只大鼠。进行了显微镜凝集试验(MAT),以检测所捕获大鼠中针对钩端螺旋体的凝集抗体的存在。所有MAT阳性的大鼠均被鉴定为蒂曼尼鼠。在吉兰丹州,17.3%(14/81)的大鼠具有针对出血性黄疸型(12.3%)、犬型(2.5%)、拜伦型(1.2%)和致热型(1.2%)血清型的钩端螺旋体抗体。在登嘉楼州,18.4%(16/87)的大鼠具有针对出血性黄疸型(15%)、犬型(1.1%)、致热型(1.1%)和七日热型(1.1%)血清型的抗体。这项研究表明,钩端螺旋体血清型在研究区域的大鼠种群中普遍存在,可能是人类的感染源。因此,控制所有国民服役训练中心的大鼠种群对于预防国民服役训练中心学员中的钩端螺旋体病暴发至关重要。

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