Garba Bashiru, Bahaman Abdul Rani, Khairani-Bejo Siti, Zakaria Zunita, Mutalib Abdul Rahim
Department of Veterinary Pathology and Microbiology, Faculty of Veterinary Medicine, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia.
Department of Veterinary Laboratory Services Unit, Faculty of Veterinary Medicine, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia.
Ecohealth. 2017 Jun;14(2):389-398. doi: 10.1007/s10393-017-1234-0. Epub 2017 Apr 12.
Leptospirosis is a bacterial disease transmitted to humans and animals by direct or indirect contact with urine or body fluids from infected animals especially rodents. Infection can be associated with wide clinical spectrum varying from asymptomatic to severe multi-organ syndrome with life-threatening consequences. We conducted a review of published studies on incidences, case reports, sero-epidemiological surveys from year 2000 to 2015 using different electronic data bases. Our study revealed that majority of the studies were conducted in Peninsular Malaysia and predominantly among high-risk human groups. Most of the studies on domestic animals were conducted in the 1980s; hence, the current status of leptospirosis among domestic animal population remains largely unknown. There tend to be a sharp rise in incidence rate among human population in the year 2014 which was attributed to flooding and heavy rainfall experienced as well as recreational activities. Several gaps in epidemiological knowledge were also disclosed.
钩端螺旋体病是一种细菌疾病，通过直接或间接接触受感染动物（尤其是啮齿动物）的尿液或体液传播给人类和动物。感染可伴有广泛的临床症状，从无症状到严重的多器官综合征，可导致危及生命的后果。我们使用不同的电子数据库，对2000年至2015年发表的关于发病率、病例报告、血清流行病学调查的研究进行了综述。我们的研究表明，大多数研究是在马来西亚半岛进行的，主要针对高危人群。大多数关于家畜的研究是在20世纪80年代进行的；因此，家畜群体中钩端螺旋体病的现状在很大程度上仍然未知。2014年人群发病率往往急剧上升，这归因于当时经历的洪水和暴雨以及娱乐活动。还揭示了流行病学知识方面的几个空白。
