Department of Pathology, Vestfold County Hospital, Halfdan Wilhelmsens Alle' 17, N-3116 Tønsberg, Norway.
Diagn Pathol. 2010 Jun 17;5:37. doi: 10.1186/1746-1596-5-37.
This case describes an infiltrating breast tumour with thyroid transcription factor-1 (TTF-1) positive staining and ductal differentiation in a 72-year-old woman. The presence of ductal carcinoma in situ with positive TTF-1 is a strong indication that this is a primary tumour and not a metastasis from lung.On PET scan and CT follow up there were no other tumours found in this patient. We are not aware of any previously reported TTF-1 positive primary breast carcinoma with ductal differentiation.
本病例描述了一位 72 岁女性的浸润性乳腺肿瘤，其甲状腺转录因子-1（TTF-1）阳性染色和导管分化。原位导管癌中 TTF-1 阳性强烈提示这是原发性肿瘤，而不是来自肺部的转移。在 PET 扫描和 CT 随访中，未在该患者中发现其他肿瘤。我们尚未发现任何先前报道的 TTF-1 阳性伴导管分化的原发性乳腺癌。
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