Arabmotlagh M, Rauschmann M
Orthopädische Universitätsklinik Friedrichsheim gGmbH, Marienburger Strasse 2, 60528, Frankfurt/M., Deutschland.
Orthopade. 2010 Jul;39(7):687-92. doi: 10.1007/s00132-010-1619-z.
In the recent years augmentation of vertebral compression fracture has been widely used with satisfactory clinical results. The filler materials for use in vertebral body augmentation have to meet many requirements. They should be biocompatible, be able to stabilize the fractured vertebral body, and their biomechanical properties should approximate those of cancellous bone. Furthermore, for a minimally invasive method that involves percutaneous injection of bone substitutes, the materials should be injectable and possess good radiopacity for the fluoroscopically guided procedure. At the present, polymethylmethacrylate is the most commonly used filler material for vertebral body augmentation. Due to the lack of bioactivity of polymethylmethacrylate that remains as an inert material in the bony tissue, new resorbable filler materials like calcium phosphate cement are increasingly in the focus of interest. In the following paper, the currently used filler materials for vertebral body augmentation and their characteristics are presented.
近年来，椎体强化术已被广泛应用，临床效果令人满意。用于椎体强化的填充材料必须满足许多要求。它们应具有生物相容性，能够稳定骨折的椎体，并且其生物力学性能应接近松质骨。此外，对于涉及经皮注射骨替代物的微创方法，材料应可注射，并在荧光镜引导手术中具有良好的射线不透性。目前，聚甲基丙烯酸甲酯是椎体强化最常用的填充材料。由于聚甲基丙烯酸甲酯缺乏生物活性，在骨组织中仍为惰性材料，像磷酸钙骨水泥这样的新型可吸收填充材料越来越受到关注。在接下来的文章中，将介绍目前用于椎体强化的填充材料及其特性。
