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The role of allergen exposure and avoidance in asthma.变应原暴露与回避在哮喘中的作用。
Adolesc Med State Art Rev. 2010 Apr;21(1):57-71, viii-ix.
2
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3
Avoidance of allergens as an environmental method in the prevention of inhaled allergy symptoms.避免过敏原作为预防吸入性过敏症状的环境方法。
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4
Results of a home-based environmental intervention among urban children with asthma.城市哮喘儿童居家环境干预的结果
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5
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6
High allergen exposure as a risk factor for asthma and allergic disease.高过敏原暴露作为哮喘和过敏性疾病的一个风险因素。
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引用本文的文献

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Puriton attenuates the asthma severity in ovalbumin-induced murine model via balancing Th1/Th2 and inhibiting inflammation.Puriton通过平衡Th1/Th2和抑制炎症来减轻卵清蛋白诱导的小鼠模型中的哮喘严重程度。
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Oleic acid attenuates asthma pathogenesis via Th1/Th2 immune cell modulation, TLR3/4-NF-κB-related inflammation suppression, and intrinsic apoptotic pathway induction.油酸通过调节 Th1/Th2 免疫细胞、TLR3/4-NF-κB 相关炎症抑制和内在凋亡途径来减轻哮喘发病机制。
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本文引用的文献

1
Air filters and air cleaners: rostrum by the American Academy of Allergy, Asthma & Immunology Indoor Allergen Committee.空气过滤器和空气净化器:美国过敏、哮喘和免疫学会室内过敏原委员会的演讲。
J Allergy Clin Immunol. 2010 Jan;125(1):32-8. doi: 10.1016/j.jaci.2009.08.036. Epub 2009 Nov 11.
2
Cats and dogs and the risk of atopy in childhood and adulthood.猫、狗与儿童及成人患特应性疾病的风险
J Allergy Clin Immunol. 2009 Oct;124(4):745-50.e4. doi: 10.1016/j.jaci.2009.06.038. Epub 2009 Aug 22.
3
Mouse allergens in urban elementary schools and homes of children with asthma.城市小学及哮喘患儿家中的小鼠过敏原。
Ann Allergy Asthma Immunol. 2009 Feb;102(2):125-30. doi: 10.1016/S1081-1206(10)60242-6.
4
Allergen avoidance in the treatment of asthma: problems with the meta-analyses.变应原回避在哮喘治疗中的应用:荟萃分析存在的问题。
J Allergy Clin Immunol. 2008 Oct;122(4):694-696. doi: 10.1016/j.jaci.2008.07.045.
5
Exotic pet allergy.外来宠物过敏。
J Allergy Clin Immunol. 2009 Feb;123(2):513-5. doi: 10.1016/j.jaci.2008.09.019. Epub 2008 Nov 2.
6
Expired nitric oxide and airway reactivity in infants at risk for asthma.哮喘高危婴儿的呼出一氧化氮与气道反应性
J Allergy Clin Immunol. 2008 Oct;122(4):760-765. doi: 10.1016/j.jaci.2008.07.022. Epub 2008 Aug 28.
7
Effect of mouse allergen and rodent environmental intervention on asthma in inner-city children.小鼠变应原和啮齿动物环境干预对市中心儿童哮喘的影响。
Ann Allergy Asthma Immunol. 2008 Jul;101(1):35-41. doi: 10.1016/S1081-1206(10)60832-0.
8
House dust mite control measures for asthma: systematic review.用于哮喘的屋尘螨控制措施:系统评价
Allergy. 2008 Jun;63(6):646-59. doi: 10.1111/j.1398-9995.2008.01690.x.
9
House dust mite control measures for asthma.哮喘的屋尘螨控制措施
Cochrane Database Syst Rev. 2008 Apr 16;2008(2):CD001187. doi: 10.1002/14651858.CD001187.pub3.
10
Cat ownership is a risk factor for the development of anti-cat IgE but not current wheeze at age 5 years in an inner-city cohort.在一个市中心城区队列中,养猫是5岁时产生抗猫免疫球蛋白E的一个风险因素,但不是当前喘息的风险因素。
J Allergy Clin Immunol. 2008 Apr;121(4):1047-52. doi: 10.1016/j.jaci.2008.02.005.

变应原暴露与回避在哮喘中的作用。

The role of allergen exposure and avoidance in asthma.

作者信息

Baxi Sachin N, Phipatanakul Wanda

机构信息

Division of Immunology, Children's Hospital, Boston/Harvard Medical School, 300 Longwood Avenue, Fegan 6, Boston, MA 02445, USA.

出版信息

Adolesc Med State Art Rev. 2010 Apr;21(1):57-71, viii-ix.

PMID:20568555
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2975603/
Abstract

Allergy testing and avoidance of allergens plays an important role in asthma control. Increased allergen exposure, in genetically susceptible individuals, can lead to allergic sensitization. Continued allergen exposure can increase the risk of asthma and other allergic diseases. In a patient with persistent asthma, identification of indoor and outdoor allergens and subsequent avoidance can improve symptoms. Often times, a patient will have multiple allergies and the avoidance plan should target all positive allergens. Several studies have shown that successful allergen remediation includes a comprehensive approach including education, cleaning, physical barriers, and maintaining these practices.

摘要

过敏测试及避免接触过敏原在哮喘控制中起着重要作用。对于基因易感性个体,增加过敏原暴露会导致过敏致敏。持续接触过敏原会增加患哮喘及其他过敏性疾病的风险。对于持续性哮喘患者,识别室内和室外过敏原并随后加以避免可改善症状。通常,患者会有多种过敏,避免计划应针对所有阳性过敏原。多项研究表明,成功的过敏原整治包括一种综合方法,涵盖教育、清洁、物理屏障以及维持这些做法。