ESHRE Central Office, Meerstraat 60, B-1852 Grimbergen, Belgium.
Hum Reprod. 2010 Aug;25(8):1851-62. doi: 10.1093/humrep/deq124. Epub 2010 Jun 22.
In this 10th European IVF-monitoring (EIM) report, the results of assisted reproductive techniques from treatments initiated in Europe during 2006 are presented. Data were mainly collected from existing national registers.
From 32 countries, 998 clinics reported 458 759 treatment cycles including: IVF (117 318), ICSI (232 844), frozen embryo replacement (FER, 86 059), egg donation (ED, 12 685), preimplantation genetic diagnosis/screening (6561), in vitro maturation (247) and frozen oocytes replacements (3498). Overall this represents a 9.7% increase in activity since 2005, which is partly due to an increase in registers (seven more countries with complete coverage). European data on intrauterine insemination using husband/partner's (IUI-H) and donor (IUI-D) semen were reported from 22 countries. A total of 134 261 IUI-H and 24 339 IUI-D cycles were included.
In 20 countries, where all clinics reported to the IVF register, a total of 359 110 assisted reproductive technology (ART) cycles were performed in a population of 422.5 million, corresponding to 850 cycles per million inhabitants. For IVF, the clinical pregnancy rates per aspiration and per transfer were 29.0 and 32.4%, respectively. For ICSI, the corresponding rates were 29.9 and 33.0%. After IUI-H the delivery rate was 9.2% in women below 40. After IVF and ICSI the distribution of transfer of one, two, three and four or more embryos was 22.1, 57.3, 19.0 and 1.6%, respectively. Compared with 2005, fewer embryos were replaced per transfer, but significant national differences in practice were apparent. The proportion of singleton, twin and triplet deliveries after IVF and ICSI combined was 79.2, 19.9 and 0.9%, respectively. This gives a total multiple delivery rates of 20.8% compared with 21.8% in 2005 and 22.7% in 2004. IUI-H in women below 40 years of age resulted in 10.6% twin and 0.6% triplet pregnancies.
Compared with previous years, the reported number of ART cycles in Europe has increased, pregnancy rates have increased marginally, even though fewer embryos were transferred and the multiple delivery rates have declined.
在这份第十届欧洲体外受精监测（EIM）报告中，呈现了 2006 年在欧洲启动的辅助生殖技术治疗的结果。数据主要来自现有的国家登记处。
来自 32 个国家的 998 家诊所报告了 458759 个治疗周期，包括：体外受精（IVF，117318 个）、胞浆内单精子注射（ICSI，232844 个）、冷冻胚胎替换（FER，86059 个）、卵子捐赠（ED，12685 个）、植入前遗传诊断/筛查（PGD/PGS，6561 个）、体外成熟（IVM，247 个）和冷冻卵母细胞替换（3498 个）。与 2005 年相比，这代表着活动量增加了 9.7%，部分原因是登记处的增加（有七个国家的登记处涵盖范围更全面）。22 个国家报告了使用丈夫/伴侣（IUI-H）和供体（IUI-D）精液的宫腔内人工授精的欧洲数据。共纳入了 134261 个 IUI-H 和 24339 个 IUI-D 周期。
在 20 个所有诊所都向 IVF 登记处报告的国家中，在 422500 万人口中进行了总计 359110 个辅助生殖技术（ART）周期，相当于每百万居民 850 个周期。对于 IVF，每个抽吸和每个转移的临床妊娠率分别为 29.0%和 32.4%。对于 ICSI，相应的比率分别为 29.9%和 33.0%。在 40 岁以下的女性中，IUI-H 的分娩率为 9.2%。在 IVF 和 ICSI 之后，一、二、三、四个或更多胚胎的转移分布分别为 22.1%、57.3%、19.0%和 1.6%。与 2005 年相比，每次转移的胚胎数量减少，但明显存在国家间的实践差异。IVF 和 ICSI 联合后的单胎、双胞胎和三胞胎分娩比例分别为 79.2%、19.9%和 0.9%。这使得总多胎分娩率为 20.8%，而 2005 年为 21.8%，2004 年为 22.7%。在 40 岁以下的女性中进行 IUI-H 会导致 10.6%的双胞胎和 0.6%的三胞胎妊娠。
与往年相比，欧洲报告的 ART 周期数量有所增加，妊娠率略有上升，尽管转移的胚胎数量减少，多胎分娩率下降。
