Nyboe Andersen A, Goossens V, Bhattacharya S, Ferraretti A P, Kupka M S, de Mouzon J, Nygren K G
ESHRE Central Office, Meerstraat 60 B-1852, Grimbergen, Belgium.
Hum Reprod. 2009 Jun;24(6):1267-87. doi: 10.1093/humrep/dep035. Epub 2009 Feb 18.
Results of assisted reproductive techniques from treatments initiated in Europe during 2005 are presented in this ninth report. Data were mainly collected from existing national registers.
From 30 countries, 923 clinics reported 418 111 treatment cycles including: IVF (118 074), ICSI (203 329), frozen embryo replacement (79 140), oocyte donation (ED, 11 475), preimplantation genetic diagnosis/screening (5846) and in vitro maturation (247). Overall, this represents a 13.6% increase since 2004, partly due to inclusion of 28 417 cycles from Turkey. European data on intrauterine insemination using husband/partner's semen (IUI-H) and donor semen (IUI-D) were reported from 21 countries and included 128 908 IUI-H and 20 568 IUI-D cycles.
In 16 countries where all clinics reported to the IVF register, 1115 cycles were performed per million inhabitants. For IVF, the clinical pregnancy rates per aspiration and per transfer were 26.9% and 30.3%, respectively. For ICSI, the corresponding rates were 28.5% and 30.9%. After IUI-H, the clinical pregnancy rate was 12.6% per insemination in women <40. After IVF and ICSI, the distribution of transfer of one, two, three and four or more embryos was 20.0%, 56.1%, 21.5% and 2.3%, respectively. Huge differences exist between countries. The distribution of singleton, twin and triplet deliveries after IVF and ICSI was 78.2%, 21.0% and 0.8%, respectively. This gives a total multiple delivery rate of 21.8% compared with 22.7% in 2004 and 23.1% in 2003. In women <40 years of age, IUI-H was associated with a twin and triplet pregnancy rate of 11.0% and 1.1%, respectively.
Compared with earlier years, there was an increase in the reported number of ART cycles in Europe. Although fewer embryos were transferred per treatment, there was a marginal increase in pregnancy rates and a reduction in multiple deliveries.
本第九次报告展示了2005年在欧洲启动的辅助生殖技术治疗结果。数据主要从现有的国家登记处收集。
来自30个国家的923家诊所报告了418111个治疗周期，包括：体外受精（IVF，118074个）、卵胞浆内单精子注射（ICSI，203329个）、冻融胚胎移植（79140个）、卵母细胞捐赠（ED，11475个）、植入前基因诊断/筛查（5846个）和体外成熟（247个）。总体而言，自2004年以来增加了13.6%，部分原因是纳入了来自土耳其的28417个周期。来自21个国家报告了使用丈夫/伴侣精液（IUI-H）和供体精液（IUI-D）的宫内人工授精的欧洲数据，包括128908个IUI-H周期和20568个IUI-D周期。
在所有诊所均向IVF登记处报告的16个国家中，每百万居民进行了1115个周期的治疗。对于IVF，每次取卵和每次移植的临床妊娠率分别为26.9%和30.3%。对于ICSI，相应的比率分别为28.5%和30.9%。在IUI-H后，40岁以下女性每次授精的临床妊娠率为12.6%。在IVF和ICSI后，移植1个、2个、3个和4个或更多胚胎的分布分别为20.0%、56.1%、21.5%和2.3%。各国之间存在巨大差异。IVF和ICSI后单胎、双胎和三胎分娩的分布分别为78.2%、21.0%和0.8%。这使得总的多胎分娩率为21.8%，而2004年为22.7%，2003年为23.1%。在40岁以下的女性中，IUI-H的双胎和三胎妊娠率分别为11.0%和1.1%。
与前些年相比，欧洲报告的辅助生殖技术周期数有所增加。尽管每次治疗移植的胚胎较少，但妊娠率略有上升，多胎分娩有所减少。
