Department of Dermatology, Chung-Ang University College of Medicine, Seoul, Korea.
Dermatol Surg. 2010 Aug;36(8):1281-7. doi: 10.1111/j.1524-4725.2010.01623.x. Epub 2010 Jun 22.
Acne is a common condition, seen in up to 80% of people aged 11 to 30. In some patients, it can result in permanent scars that are surprisingly difficult to treat, with current treatments for acne scars having limited efficacy. Recently, subdermal minimal surgery technology has been introduced as a novel therapeutic modality for acne scars.
To evaluate the clinical efficacy and safety of subdermal minimal surgery technology for treating acne scars.
Ten Korean patients (Fitzpatrick skin type II-V) with acne scars were enrolled in this study. They received three sessions of subdermal minimal surgery technology at 4-week intervals. The treatment parameters were a one-shot 0.15-mL volume of hyaluronic acid (HA) and 70% pressure power with a 10- x 10-mm square-shaped tip. Two independent dermatologists evaluated clinical improvement using a quartile grading scale by comparing digital photographs taken before treatment (baseline) and 3 months after the last treatment. The patients also evaluated any side effects at each visit. At the end of the study, the patients documented pain severity (none, mild, moderate, or severe) during the procedure and degree of satisfaction (worse, no change, mild, moderate, or strong improvement).
All volunteers completed the three treatment sessions and were satisfied with the procedure. Three months after the last treatment session, according to the physicians' assessments, two patients had improvement of greater than 75% in acne scars, six had 50% to 75% improvement, and two had 25% to 50% improvement. Patient degree of satisfaction was similar to the physicians' assessment. There were no side effects except transient spot bleeding at entry points and slight edema that resolved within 48 hours.
Subdermal minimal surgery technology is an effective and safe method for improving acne scars.
痤疮是一种常见疾病，多达 80%的 11 至 30 岁人群会发病。在某些患者中，痤疮可导致永久性疤痕，这些疤痕极难治疗，而目前针对痤疮疤痕的治疗方法疗效有限。最近，皮下微创技术已被引入作为一种治疗痤疮疤痕的新方法。
评估皮下微创技术治疗痤疮疤痕的临床疗效和安全性。
本研究纳入了 10 名韩国痤疮疤痕患者（Fitzpatrick 皮肤类型 II-V）。他们接受了 3 次皮下微创技术治疗，每次治疗间隔 4 周。治疗参数为单次注射 0.15 毫升透明质酸（HA），压力功率为 70%，使用 10x10 毫米方形尖端。两名独立的皮肤科医生使用四分位等级量表，通过比较治疗前（基线）和最后一次治疗后 3 个月的数字照片来评估临床改善情况。患者还在每次就诊时评估任何不良反应。在研究结束时，患者记录了手术过程中的疼痛严重程度（无、轻度、中度或重度）和满意度（更差、无变化、轻度、中度或明显改善）。
所有志愿者都完成了 3 次治疗，对该过程均感到满意。最后一次治疗 3 个月后，根据医生的评估，2 名患者的痤疮疤痕改善程度大于 75%，6 名患者的改善程度为 50%至 75%，2 名患者的改善程度为 25%至 50%。患者的满意度与医生的评估相似。除了入口处的短暂点状出血和轻微的水肿外，没有其他不良反应，这些水肿在 48 小时内消退。
皮下微创技术是改善痤疮疤痕的有效且安全的方法。
