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肱骨髁上骨折移位手术治疗后医源性尺神经损伤:伤害需治病例数,一项系统评价

Iatrogenic ulnar nerve injury after the surgical treatment of displaced supracondylar fractures of the humerus: number needed to harm, a systematic review.

作者信息

Slobogean Bronwyn L, Jackman Heather, Tennant Sally, Slobogean Gerard P, Mulpuri Kishore

机构信息

Department of Orthopaedics, BC Children's Hospital, Vancouver, British Columbia, Canada.

出版信息

J Pediatr Orthop. 2010 Jul-Aug;30(5):430-6. doi: 10.1097/BPO.0b013e3181e00c0d.

Abstract

BACKGROUND

Supracondylar fractures of the humerus are common pediatric elbow injuries. Most displaced or angulated fractures are treated by closed reduction and percutaneous pinning, with either a crossed pin or lateral pin configuration. The purpose of this study was to conduct a systematic review to determine if there is an increased risk of iatrogenic nerve injury associated with the crossed pin configuration.

METHODS

Relevant articles were identified by searching electronic databases and hand searching-related journal and conference proceedings. Within each trial, the risk of iatrogenic ulnar nerve injury was calculated for each pinning technique. For studies comparing crossed versus lateral pinning, the resulting trial-based differences in risk estimates were pooled using a random effects meta-analysis. A number needed to harm was determined using the pooled risk difference.

RESULTS

Thirty-two trials consisting of 2639 patients were used in the pooled analysis. The pooled risk difference of iatrogenic ulnar nerve injury is 0.035 (95% confidence interval, 0.014-0.056), with a higher incidence of injury in the crossed pinning group. The weighed number needed to harm for the crossed pinning is 28 (95% confidence interval, 17-71).

CONCLUSIONS

The results of this review suggest that there is an iatrogenic ulnar nerve injury for every 28 patients treated with the crossed pinning compared with the lateral pinning. Further research is necessary to ensure that the optimal pinning technique is chosen to treat these factors.

LEVEL OF EVIDENCE

Level III.

摘要

背景

肱骨髁上骨折是常见的小儿肘部损伤。大多数移位或成角骨折采用闭合复位和经皮穿针固定治疗,穿针方式可为交叉穿针或外侧穿针。本研究的目的是进行一项系统评价,以确定交叉穿针固定方式是否会增加医源性神经损伤的风险。

方法

通过检索电子数据库以及手工检索相关期刊和会议论文集来识别相关文章。在每个试验中,计算每种穿针技术导致医源性尺神经损伤的风险。对于比较交叉穿针与外侧穿针的研究,使用随机效应荟萃分析汇总基于试验得出的风险估计差异。使用汇总风险差异确定伤害所需人数。

结果

汇总分析纳入了32项试验,共2639例患者。医源性尺神经损伤的汇总风险差异为0.035(95%置信区间,0.014 - 0.056),交叉穿针组的损伤发生率更高。交叉穿针的加权伤害所需人数为28(95%置信区间,17 - 71)。

结论

本评价结果表明,与外侧穿针相比,每28例接受交叉穿针治疗的患者中就有1例发生医源性尺神经损伤。有必要进行进一步研究,以确保选择最佳的穿针技术来处理这些因素。

证据级别

三级。

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