School of Medical Science and Laboratory Medicine, Jiangsu University, 301 Xuefu Road, Zhenjiang, Jiangsu, People's Republic of China.
Arch Virol. 2010 Sep;155(9):1493-6. doi: 10.1007/s00705-010-0733-x. Epub 2010 Jun 25.
Recombination of mumps virus (MuV) has rarely been reported. In this study, phylogenetic and recombination analyses were performed on 30 complete MuV genomes, including 17 vaccine and 13 wild-type strains. One potentially significant recombination event was found to have occurred between the lineage represented by the vaccine strain L3/Russia/Vector (AY508995) as the minor parent and wild MuV strain Drag94 (AY669145) as the major parent, and this led to a recombinant, 9218/Zg98 (EU370206), a wild-type MuV strain isolated from a 3-year-old boy with parotitis. In summary, we found a recombinant of MuV derived from vaccine and wild-type MuV strains.
腮腺炎病毒（MuV）的重组很少有报道。在这项研究中，对 30 株完整的 MuV 基因组，包括 17 株疫苗株和 13 株野生型株，进行了系统进化和重组分析。发现一个潜在的重要重组事件发生在疫苗株 L3/Russia/Vector（AY508995）作为次要亲本和野生型 MuV 株 Drag94（AY669145）作为主要亲本之间，这导致了一个重组株 9218/Zg98（EU370206）的产生，该重组株是从一名 3 岁患有腮腺炎的男孩中分离出来的野生型 MuV 株。总之，我们发现了一个由疫苗株和野生型 MuV 株衍生的 MuV 重组株。
