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肯尼亚尼扬扎省城乡地区的散发性儿童腹泻病

Sporadic paediatric diarrhoeal illness in urban and rural sites in Nyanza Province, Kenya.

作者信息

Beatty M E, Ochieng J B, Chege W, Kumar L, Okoth G, Shapiro R L, Wells J G, Parsons M B, Bopp C, Chiller T, Vulule J, Mintz E, Slutsker L, Brooks J T

机构信息

Division of Foodborne, Bacterial and Mycotic Diseases, National Center for Zoonotic, Vectorborne, and Enteric Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.

出版信息

East Afr Med J. 2009 Aug;86(8):387-98. doi: 10.4314/eamj.v86i8.54159.

Abstract

OBJECTIVE

Investigate differences in the infectious aetiology, health seeking behaviour, and provider practices with regard to diarrhoeal illness among children presenting to urban versus rural clinics in Western Kenya.

DESIGN

Laboratory-based, passive surveillance.

SETTING

The urban portion of the study was conducted at the paediatric outpatient clinic of Nyanza Provincial Hospital in Kisumu. The rural portion of the study was conducted at four outpatient clinics in the Asembo Bay community approximately 20 kilometers west of Kisumu.

SUBJECTS

Children aged less than five years presenting to medical facilities for the treatment of diarrhoea from October 2001-October 2003 at the urban site and May 1997-April 2003 for the rural sites.

RESULTS

Among the 1303 urban and 1247 rural specimens collected, 24% of specimens yielded a bacterial pathogen (24% urban, 25% rural). Campylobacter was the predominant bacterial pathogen (17% urban, 15% rural), followed by Shigella and nontyphoidal Salmonella (both 4% urban and 5% rural). In both communities, susceptibilities of these pathogens to the most commonly prescribed antibiotics was low (< or = 50%); 70% of all episodes of diarrhoea were prescribed antibiotic treatment. Urban health practitioners prescribed fewer antibiotics, chose drugs more likely to be effective, and were more likely to prescribe oral rehydration therapy for bloody diarrhoea.

CONCLUSION

Most characteristics of diarrhoeal disease and their causes were similar in paediatric patients presenting to urban and rural clinics. Urban providers were more compliant with WHO recommendations.

摘要

目的

调查肯尼亚西部城市和农村诊所中因腹泻就诊儿童在感染病因、就医行为及医疗服务提供者诊疗行为方面的差异。

设计

基于实验室的被动监测。

地点

研究的城市部分在基苏木市尼亚萨省医院的儿科门诊进行。研究的农村部分在基苏木以西约20公里的阿森博湾社区的四个门诊进行。

研究对象

2001年10月至2003年10月在城市地区以及1997年5月至2003年4月在农村地区到医疗机构治疗腹泻的5岁以下儿童。

结果

在收集的1303份城市样本和1247份农村样本中,24%的样本检出细菌病原体(城市地区为24%,农村地区为25%)。弯曲杆菌是主要的细菌病原体(城市地区为17%,农村地区为15%),其次是志贺氏菌和非伤寒沙门氏菌(城市和农村地区均为4%和5%)。在两个社区中,这些病原体对最常用抗生素的敏感性都很低(≤50%);所有腹泻病例中有70%接受了抗生素治疗。城市的医疗从业者开具的抗生素较少,选择的药物更可能有效,并且更有可能为血性腹泻开具口服补液疗法。

结论

到城市和农村诊所就诊的儿科患者腹泻疾病的大多数特征及其病因相似。城市的医疗服务提供者更符合世界卫生组织的建议。

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