Dahiya Kiran, Aggarwal Kavita, Seth Shashi, Singh Veena, Sharma Tarun K
Department of Biochemistry, Pt. B.D.Sharma PGIMS, Rohtak, Haryana, India.
Clin Lab. 2010;56(5-6):187-90.
Ischemia modified albumin (IMA) is a proven cardiac marker but its role in type 2 diabetes mellitus without vascular complications has not been reported yet. Therefore, IMA was estimated in 60 newly diagnosed patients of type 2 diabetes mellitus and 30 healthy controls along with HbA1c and other investigations (to rule out vascular complications). There was no significant change in IMA levels in type 2 diabetic patients as compared to controls. No correlation could be found between IMA levels and HbA1c. We conclude that IMA levels are not affected in type 2 diabetes mellitus before the onset of vascular complications.
缺血修饰白蛋白（IMA）是一种经证实的心脏标志物，但它在无血管并发症的2型糖尿病中的作用尚未见报道。因此，我们对60例新诊断的2型糖尿病患者和30名健康对照者进行了IMA测定，并同时检测了糖化血红蛋白（HbA1c）及其他指标（以排除血管并发症）。与对照组相比，2型糖尿病患者的IMA水平无显著变化。IMA水平与HbA1c之间未发现相关性。我们得出结论，在血管并发症发生之前，2型糖尿病患者的IMA水平不受影响。
