Division of Vector Borne Infectious Diseases, Dengue Branch, Centers for Disease Control and Prevention, 1324 Calle Canada, San Juan, Puerto Rico.
Vector Borne Zoonotic Dis. 2011 Apr;11(4):447-50. doi: 10.1089/vbz.2010.0011. Epub 2010 Jun 24.
After the isolation of West Nile virus (WNV) from humans, mosquitoes, and chickens in 2007, an analysis of animal surveillance involving multiple species (horses, monkeys, sheep, dogs, and birds) used to track WNV transmission from 2006 to 2008 was performed. During this period 13.4% of all the animal samples collected were seropositive by blocking ELISA for WNV. The most complete island-wide sampling was obtained from horses of which 22% were serologically positive and 96% were confirmed as WNV infections by plaque-reduction neutralization test. Our conclusion from this 3-year study is that animal surveillance is an early indicator of WNV activity before the identification of human cases. Additionally, the results indicated that horses have a greater geographical range and should be continued to be used as sentinels for passive surveillance in the tropics.
2007 年，西尼罗河病毒（WNV）在人类、蚊子和鸡中被分离出来后，对 2006 年至 2008 年涉及多种物种（马、猴子、绵羊、狗和鸟类）的动物监测分析进行了跟踪WNV 传播。在此期间，通过阻断 ELISA 对所有动物样本进行检测，13.4%的动物样本呈血清阳性。通过对马进行的范围最广的全岛采样，22%的马血清学呈阳性，96%的马通过蚀斑减少中和试验被确认为 WNV 感染。我们从这项为期 3 年的研究中得出的结论是，动物监测是在确定人类病例之前WNV 活动的早期指标。此外，结果表明马的地理范围更广，应继续作为热带地区被动监测的哨兵。
