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病理性皮肤搔抓与强迫症的临床比较

A clinical comparison of pathologic skin picking and obsessive-compulsive disorder.

机构信息

Department of Psychiatry, Ambulatory Research Center, University of Minnesota Medical Center, Minneapolis, MN 55454, USA.

出版信息

Compr Psychiatry. 2010 Jul-Aug;51(4):347-52. doi: 10.1016/j.comppsych.2009.10.006. Epub 2009 Dec 21.

Abstract

BACKGROUND

It has been hypothesized that pathologic skin picking (PSP) shares many of the same biological and phenomenological characteristics as obsessive-compulsive disorder (OCD). This study sought to examine the clinical similarities between PSP and OCD.

METHOD

Demographic and clinical characteristic data were examined in a treatment-seeking sample of 53 PSP (mean age, 34.2 +/- 13.1 years; 86.8% female) and 51 OCD (mean age, 36.5 +/- 11.7 years; 35.3% female) subjects. Psychiatric comorbidity and family history data were also obtained.

RESULTS

The PSP subjects were more likely to be female (P < .001), report higher rates of co-occurring compulsive nail biting (P < .001), and have a first-degree relative with a grooming disorder (P < .001). The OCD subjects spent significantly more time on their thoughts and behaviors (P < .001) and were more likely to have co-occurring body dysmorphic disorder (P = .001).

CONCLUSION

Although PSP and OCD share some clinical similarities, important differences exist and cast doubt on the conceptualization of PSP as simply a variant of OCD.

摘要

背景

病理性皮肤搔抓(PSP)被认为与强迫症(OCD)具有许多相同的生物学和现象学特征。本研究旨在探讨 PSP 与 OCD 之间的临床相似性。

方法

在一个寻求治疗的 53 名 PSP(平均年龄 34.2 +/- 13.1 岁;86.8%女性)和 51 名 OCD(平均年龄 36.5 +/- 11.7 岁;35.3%女性)患者的样本中,检查了人口统计学和临床特征数据。还获得了精神共病和家族史数据。

结果

PSP 组女性患者更多(P <.001),报告并发强迫性咬指甲的比例更高(P <.001),一级亲属有梳理障碍(P <.001)。OCD 组在其思维和行为上花费的时间明显更多(P <.001),并且更可能同时患有躯体变形障碍(P =.001)。

结论

尽管 PSP 和 OCD 具有一些临床相似性,但存在重要差异,这对将 PSP 概念化为 OCD 的一种变体提出了质疑。

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