Department of Psychiatry, Federal University of Rio Grande do Sul, Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil.
Compr Psychiatry. 2012 Jul;53(5):562-8. doi: 10.1016/j.comppsych.2011.06.008. Epub 2011 Oct 19.
The objective of this study was to compare patients with obsessive-compulsive disorder (OCD) associated with pathologic skin picking (PSP) and/or trichotillomania, and patients with OCD without such comorbidities, for demographic and clinical characteristics. We assessed 901 individuals with a primary diagnosis of OCD, using the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) Axis I disorders. Diagnoses of PSP and trichotillomania were made in 16.3% and 4.9% of the sample, respectively. After the logistic regression analysis, the following factors retained an association with OCD-PSP/trichotillomania: younger (odds ratio [OR] = 0.979; P = .047), younger at the onset of compulsive symptoms (OR = 0.941; P = .007), woman (OR = 2.538; P < .001), with a higher level of education (OR = 1.055; P = .025), and with comorbid body dysmorphic disorder (OR = 2.363; P = .004). These findings support the idea that OCD accompanied by PSP/trichotillomania characterizes a specific subgroup.
本研究旨在比较伴有病理性皮肤搔抓（PSP）和/或拔毛癖的强迫症（OCD）患者与无此类共病的 OCD 患者的人口统计学和临床特征。我们使用精神障碍诊断与统计手册第四版（DSM-IV）轴 I 障碍的结构临床访谈，评估了 901 名原发性 OCD 患者。在该样本中，分别有 16.3%和 4.9%的患者被诊断为 PSP 和拔毛癖。在进行逻辑回归分析后，以下因素与 OCD-PSP/拔毛癖相关：年龄较小（比值比[OR] = 0.979；P =.047），强迫症状起始年龄较小（OR = 0.941；P =.007），女性（OR = 2.538；P <.001），受教育程度较高（OR = 1.055；P =.025），伴有躯体变形障碍（OR = 2.363；P =.004）。这些发现支持了这样一种观点，即伴有 PSP/拔毛癖的 OCD 表现为一个特定的亚组。
