Department of Urology, Columbia Medical Center, New York, New York 10032, USA.
J Endourol. 2010 Jul;24(7):1091-6. doi: 10.1089/end.2010.0132.
Carbon dioxide (CO(2)) lasers deliver energy with minimal thermal spread to tissues during dissection. Excess thermal spread during dissection of the neurovascular bundle (NVB) can affect potency in men after robot-assisted radical prostatectomy (RARP). We report on a novel delivery mechanism for CO(2) laser energy through a flexible fiber to enhance accuracy of NVB dissection during RARP.
A feasibility study of the OmniGuide BeamPath URO-LG CO(2) laser fiber for NVB dissection was performed on 10 patients with primary Gleason 3 T1c prostate cancer during RARP. Bilateral lateral fascial antegrade nerve sparing was performed. We evaluated fiber performance, safety, and efficacy.
The fiber was inserted through the 12-mm assistant's port and easily manipulated by robotic instruments. Once pedicles were clipped and dissected, the laser fiber was effective in establishing planes of dissection between prostatic capsule and NVB. The endoscopically discernable thermal laser footprint was small, with minimal thermal spread during nerve sparing, meticulous dissection of NVB, and fascial layer identification. Although the laser did provide extremely accurate dissection, it was unable to serve as an adequate means of larger vessel coagulation.
The flexible CO(2) laser fiber was easily manipulated. Identification of fascial layers during nerve sparing was facilitated with the fiber. Long-term follow-up is necessary to determine efficacy of this technology versus conventional techniques on the NVB. Larger studies are currently in progress to determine if use of the flexible CO(2) laser fiber results in improvements in functional outcomes with regard to return of sexual potency after RARP.
二氧化碳(CO(2))激光在分离组织时能以最小的热扩散输送能量。在机器人辅助根治性前列腺切除术(RARP)中,神经血管束(NVB)分离过程中过度的热扩散会影响男性的勃起功能。我们报告了一种通过柔性光纤传输 CO(2)激光能量的新型传输机制,以提高 RARP 中 NVB 分离的准确性。
对 10 例原发性 Gleason 3 T1c 前列腺癌患者的 RARP 进行了 OmniGuide BeamPath URO-LG CO(2)激光光纤用于 NVB 分离的可行性研究。行双侧侧方筋膜前向神经保留术。我们评估了纤维的性能、安全性和有效性。
光纤通过 12mm 助手端口插入,可被机器人器械轻松操作。一旦夹闭并分离了蒂,激光光纤就可以有效地在前列腺包膜和 NVB 之间建立分离平面。可在镜下辨别的热激光足迹很小,在神经保留、NVB 的精细分离和筋膜层识别过程中热扩散很小。虽然激光确实提供了极其精确的分离,但它不能作为凝固较大血管的有效手段。
柔性 CO(2)激光光纤易于操作。光纤有助于在神经保留时识别筋膜层。需要进行长期随访以确定该技术与传统技术在 NVB 方面的疗效。目前正在进行更大规模的研究,以确定使用柔性 CO(2)激光光纤是否能改善 RARP 后性功能恢复的功能结果。