Department of Neuropsychiatry, Seoul National University Bundang Hospital, Seongnam, Korea.
Psychiatry Investig. 2010 Jun;7(2):102-8. doi: 10.4306/pi.2010.7.2.102. Epub 2010 Apr 6.
We developed a Korean version of Mini-Mental Status Examination (MMSE) optimized for screening dementia (MMSE-DS) and its' short form (SMMSE-DS).
We constructed the MMSE-DS using the items of the two current Korean versions of MMSE and then construct the SMMSE-DS consisted of 13 items from the MMSE-DS based on the diagnostic accuracy of individual items for dementia. We investigated reliability and validity of MMSE-DS and SMMSE-DS on 1,555 subjects (1,222 nondemented controls, 333 dementia patients). We compared the diagnostic accuracy of the SMMSE-DS with that of the three full Korean versions of MMSE, and examined its' age- and education-specific optimal cutoff scores for dementia.
The internal consistency obtained by Cronbach's coefficient alpha was 0.826. The inter-rater reliability and test-retest reliability were 0.968 (p<0.001) and 0.825 (p<0.001), respectively. It showed significant correlation with the Clinical Dementia Rating (CDR) (r=-0.698, p<0.05) and the three full Korean versions of MMSE (r=0.839-0.938, p<0.001). The area under the receiver operator curve for dementia of the SMMSE-DS was larger than those of the three full Korean versions of MMSE (p<0.001). Age, education and gender explained 19.4% of the total variance of SMMSE-DS scores. The optimal cutoff scores for dementia of the SMMSE-DS were estimated differently by age and educational attainment of the subjects.
The SMMSE-DS was found to be accurate, brief and portable instrument for screening dementia in Korean elders, and may be particularly useful for screening dementia in elderly populations with wide variation in educational levels.
我们开发了一种经过优化的用于痴呆筛查的韩国版简易精神状态检查（MMSE），即 MMSE-DS 及其简短形式（SMMSE-DS）。
我们使用现有的两种韩国版 MMSE 的项目构建 MMSE-DS，然后根据各个项目对痴呆症的诊断准确性，从 MMSE-DS 中构建包含 13 个项目的 SMMSE-DS。我们在 1555 名受试者（1222 名非痴呆对照组，333 名痴呆患者）中研究了 MMSE-DS 和 SMMSE-DS 的可靠性和有效性。我们比较了 SMMSE-DS 与三种完整的韩国版 MMSE 的诊断准确性，并检验了其针对痴呆症的特定年龄和教育优化截断分数。
Cronbach's 系数 alpha 得到的内部一致性为 0.826。评分者间信度和重测信度分别为 0.968（p<0.001）和 0.825（p<0.001）。它与临床痴呆评定量表（CDR）（r=-0.698，p<0.05）和三种完整的韩国版 MMSE（r=0.839-0.938，p<0.001）均呈显著相关性。SMMSE-DS 对痴呆的受试者工作特征曲线下面积大于三种完整的韩国版 MMSE（p<0.001）。SMMSE-DS 评分的总方差由年龄、教育程度和性别解释了 19.4%。SMMSE-DS 对痴呆症的最佳截断分数因受试者的年龄和教育程度而异。
SMMSE-DS 是一种准确、简短且便携的用于韩国老年人痴呆筛查的工具，对于具有广泛教育水平差异的老年人群体的痴呆筛查可能特别有用。
